Risk incidence of fractures and injuries: a multicenter video-EEG study of 626 generalized convulsive seizures

التفاصيل البيبلوغرافية
العنوان: Risk incidence of fractures and injuries: a multicenter video-EEG study of 626 generalized convulsive seizures
المؤلفون: Johann Philipp Zöllner, Yulia Oganian, Lara Kay, Katja Menzler, Fee Keil, Laurent M. Willems, Susanne Knake, Felix Rosenow, Sebastian Bauer, Susanne Schubert-Bast, Katharina Frey, Katharina Mahr, Adam Strzelczyk
المصدر: Journal of Neurology
بيانات النشر: Springer Science and Business Media LLC, 2020.
سنة النشر: 2020
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Neurology, Adolescent, Video eeg, Shoulder luxation, Young Adult, 03 medical and health sciences, Epilepsy, 0302 clinical medicine, Seizures, Back pain, medicine, Humans, 030212 general & internal medicine, Child, Adverse effect, Aged, Neuroradiology, Original Communication, business.industry, Incidence, Incidence (epidemiology), Electroencephalography, Middle Aged, medicine.disease, Seizure, Fracture, Convulsive Seizures, Child, Preschool, Anesthesia, Epilepsy, Generalized, Female, Neurology (clinical), Morbidity, medicine.symptom, business, 030217 neurology & neurosurgery
الوصف: Objective To evaluate the incidence and risk factors of generalized convulsive seizure (GCS)-related fractures and injuries during video-EEG monitoring. Methods We analyzed all GCSs in patients undergoing video-EEG-monitoring between 2007 and 2019 at epilepsy centers in Frankfurt and Marburg in relation to injuries, falls and accidents associated with GCSs. Data were gathered using video material, EEG material, and a standardized reporting form. Results A total of 626 GCSs from 411 patients (mean age: 33.6 years; range 3–74 years; 45.0% female) were analyzed. Severe adverse events (SAEs) such as fractures, joint luxation, corneal erosion, and teeth loosening were observed in 13 patients resulting in a risk of 2.1% per GCS (95% CI 1.2–3.4%) and 3.2% per patient (95% CI 1.8–5.2%). Except for a nasal fracture due to a fall onto the face, no SAEs were caused by falls, and all occurred in patients lying in bed without evidence of external trauma. In seven patients, vertebral body compression fractures were confirmed by imaging. This resulted in a risk of 1.1% per GCS (95% CI 0.5–2.2%) and 1.7% per patient (95% CI 0.8–3.3%). These fractures occurred within the tonic phase of a GCS and were accompanied by a characteristic cracking noise. All affected patients reported back pain spontaneously, and an increase in pain on percussion of the affected spine section. Conclusions GCSs are associated with a substantial risk of fractures and shoulder dislocations that are not associated with falls. GCSs accompanied by audible cracking, and resulting in back pain, should prompt clinical and imaging evaluations.
تدمد: 1432-1459
0340-5354
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::119b3c683a3d932e178c28b7f7f1238d
https://doi.org/10.1007/s00415-020-10065-5
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....119b3c683a3d932e178c28b7f7f1238d
قاعدة البيانات: OpenAIRE