The Role of Uric Acid in Acute and Chronic Coronary Syndromes
| العنوان: | The Role of Uric Acid in Acute and Chronic Coronary Syndromes |
|---|---|
| المؤلفون: | Michela Algeri, Jacopo Oreglia, Nuccia Morici, Claudio Borghi, Valentina Giani, Giacomo Ruzzenenti, Sara Scarpellini, Alice Sacco, Francesco Soriano, Federica Piani, Massimiliano Monticelli, Cristina Giannattasio, Filippo Leidi, Alessandro Maloberti, Stefano Nava, Marco Biolcati, Fabrizio Oliva |
| المساهمون: | Alessandro Maloberti, Marco Biolcati, Giacomo Ruzzenenti, Valentina Giani, Filippo Leidi, Massimiliano Monticelli, Michela Algeri, Sara Scarpellini, Stefano Nava, Francesco Soriano, Jacopo Oreglia, Alice Sacco, Nuccia Morici, Fabrizio Oliva, Federica Piani, Claudio Borghi, Cristina Giannattasio, Maloberti, A, Biolcati, M, Ruzzenenti, G, Giani, V, Leidi, F, Monticelli, M, Algeri, M, Scarpellini, S, Nava, S, Soriano, F, Oreglia, J, Sacco, A, Morici, N, Oliva, F, Piani, F, Borghi, C, Giannattasio, C |
| المصدر: | Journal of Clinical Medicine, Vol 10, Iss 4750, p 4750 (2021) Journal of Clinical Medicine |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Purine, Articular gout, chronic coronary syndrome, medicine.medical_specialty, Acute coronary syndrome, business.industry, Incidence (epidemiology), Atrial fibrillation, Review, General Medicine, medicine.disease, chemistry.chemical_compound, chemistry, uric acid, Heart failure, Internal medicine, medicine, Cardiology, Medicine, Uric acid, business, Kidney disease |
| الوصف: | Uric acid (UA) is the final product of the catabolism of endogenous and exogenous purine nucleotides. While its association with articular gout and kidney disease has been known for a long time, new data have demonstrated that UA is also related to cardiovascular (CV) diseases. UA has been identified as a significant determinant of many different outcomes, such as all-cause and CV mortality, and also of CV events (mainly Acute Coronary Syndromes (ACS) and even strokes). Furthermore, UA has been related to the development of Heart Failure, and to a higher mortality in decompensated patients, as well as to the onset of atrial fibrillation. After a brief introduction on the general role of UA in CV disorders, this review will be focused on UA’s relationship with CV outcomes, as well as on the specific features of patients with ACS and Chronic Coronary Syndrome. Finally, two issues which remain open will be discussed: the first is about the identification of a CV UA cut-off value, while the second concerns the possibility that the pharmacological reduction of UA is able to lower the incidence of CV events. |
| وصف الملف: | STAMPA |
| اللغة: | English |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12bd8fe5ad9e656b489d9096236a775f https://hdl.handle.net/11585/848010 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....12bd8fe5ad9e656b489d9096236a775f |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |