Clinical Characteristics and Prognosis of Incidentally Detected Lung Cancers
| العنوان: | Clinical Characteristics and Prognosis of Incidentally Detected Lung Cancers |
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| المؤلفون: | Domingo Chimondeguy, Silvia Quadrelli, Gustavo Lyons, Agustín Buero, Henri G. Colt |
| المصدر: | International Journal of Surgical Oncology, Vol 2015 (2015) International Journal of Surgical Oncology |
| بيانات النشر: | Hindawi Limited, 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Male, Lung Neoplasms, medicine.medical_treatment, Kaplan-Meier Estimate, Gastroenterology, Carcinoma, Non-Small-Cell Lung, 80 and over, Non-Small-Cell Lung, Pneumonectomy, Lung, Cancer, Aged, 80 and over, Incidental Findings, Lung Cancer, Middle Aged, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Prognosis, Survival Rate, Oncology, Carcinoma, Squamous Cell, Adenocarcinoma, Female, medicine.symptom, Research Article, Adult, medicine.medical_specialty, Article Subject, Malignancy, lcsh:RC254-282, Asymptomatic, Clinical Research, Internal medicine, medicine, Humans, Lung cancer, Survival rate, Retrospective Studies, Aged, Solitary pulmonary nodule, business.industry, Carcinoma, Retrospective cohort study, medicine.disease, Surgery, Good Health and Well Being, Squamous Cell, business |
| الوصف: | Objective. To evaluate clinical characteristics and outcomes in incidentally detected lung cancer and in symptomatic lung cancer.Material and Methods. We designed a retrospective study including all patients undergoing pulmonary resection with a curative intention for NSCLC. They were classified into two groups according to the presence or absence of cancer-related symptoms at diagnosis in asymptomatic (ASX)—incidental diagnosis—or symptomatic.Results. Of the 593 patients, 320 (53.9%) were ASX. In 71.8% of these, diagnosis was made by chest X-ray. Patients in the ASX group were older (P=0.007), had a higher prevalence of previous malignancy (P=0.002), presented as a solitary nodule more frequently (P<0.001), and were more likely to have earlier-stage disease and smaller cancers (P=0.0001). A higher prevalence of incidental detection was observed in the last ten years (P=0.008). Overall 5-year survival was higher for ASX (P=0.001). Median survival times in pathological stages IIIB-IV were not significantly different.Conclusion. Incidental finding of NSCLC is not uncommon even among nonsmokers. It occurred frequently in smokers and in those with history of previous malignancy. Mortality of incidental diagnosis group was lower, but the better survival was related to the greater number of patients with earlier-stage disease. |
| وصف الملف: | application/pdf; text/xhtml |
| تدمد: | 2090-1410 2090-1402 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12d0430a2bffe10f45c5b0705cf49737 https://doi.org/10.1155/2015/287604 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....12d0430a2bffe10f45c5b0705cf49737 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20901410 20901402 |
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