Context:Use of root canal solvents has increased the success rate of endodontic retreatment and it has made the procedure faster and simpler. Aims: During retreatment, a solvent facilitates the removal of obturation material and root canal sealer by softening it, so as to obtain a root canal free of debris and microorganisms. Hence an invitro study was done to evaluate and compare the dissolving effect of RC Solve, Eucalyptus oil and G-sol on AH Plus Root Canal Sealer. Methods and Material: Thirty standardized stainless-steel rings filled with AH Plus sealer manipulated according to manufacturers instructions were prepared and placed ten minutes for complete setting in an incubator at 37°C for 48 hours and weighed to obtain the initial weight. The samples were divided into three equal groups of 10 each and immersed in RC Solve, Eucalyptus oil and G-sol for 10 minutes and dried in an incubator at 37°C for 24 hours and weighed again for final weight. The amount of sealer lost was determined by calculating the difference between initial and final weight. Results:The dissolving effect of AH Plus sealer on all three solvents showed a marked amount of weight loss (p Conclusions:Based on the findings of this study, it was concluded that Eucalyptus oil has a slightly better solvent effect.