Unusual case of Epstein-Barr virus DNA tissue positive: Blood negative in a patient with post-transplant lymphoproliferative disorder
| العنوان: | Unusual case of Epstein-Barr virus DNA tissue positive: Blood negative in a patient with post-transplant lymphoproliferative disorder |
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| المؤلفون: | Deborah A. Payne, Naveen K. Mittal, Charles F. Timmons, Sabina Ali, Alagarraju Muthukumar, Brian M. Levenson |
| المصدر: | Pediatric Transplantation. 13:134-138 |
| بيانات النشر: | Wiley, 2009. |
| سنة النشر: | 2009 |
| مصطلحات موضوعية: | Graft Rejection, Herpesvirus 4, Human, Pathology, medicine.medical_specialty, Pcr assay, Early detection, In situ hybridization, Methylprednisolone, Polymerase Chain Reaction, Post-transplant lymphoproliferative disorder, hemic and lymphatic diseases, Humans, Medicine, Lymphocytes, Child, Lymph node, Transplantation, Unusual case, business.industry, Epstein-Barr virus DNA, Immunoglobulins, Intravenous, Viral Load, medicine.disease, Virology, Lymphoproliferative Disorders, Liver Transplantation, surgical procedures, operative, medicine.anatomical_structure, Tissue sections, DNA, Viral, Pediatrics, Perinatology and Child Health, Female, business |
| الوصف: | Detection of PTLD uses PCR to detect circulating EBV DNA in the blood or in situ hybridization to identify EBV DNA in tissue biopsies. EBV DNA was detected in the tissue section using both real-time PCR and in situ hybridization. We report an unusual presentation of PTLD with no detectable EBV DNA in the blood using EBER-1 and EBNA-1 PCR assays. This report suggests that the use of EBV-PCR for the early detection of PTLD in blood samples may not be 100% effective in detecting disease. |
| تدمد: | 1399-3046 1397-3142 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12ddbb6e2f76ff0e61120d2e9650a509 https://doi.org/10.1111/j.1399-3046.2008.00965.x |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....12ddbb6e2f76ff0e61120d2e9650a509 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13993046 13973142 |
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