Atherosclerotic plaque volume and composition in symptomatic carotid arteries assessed with multidetector CT angiography; relationship with severity of stenosis and cardiovascular risk factors
| العنوان: | Atherosclerotic plaque volume and composition in symptomatic carotid arteries assessed with multidetector CT angiography; relationship with severity of stenosis and cardiovascular risk factors |
|---|---|
| المؤلفون: | S. Rozie, Diederik W.J. Dippel, T.T. de Weert, Hervé L. J. Tanghe, C. de Monye, Philip J. Homburg, A. van der Lugt |
| المساهمون: | Radiology & Nuclear Medicine, Neurology |
| المصدر: | European Radiology, 19(9), 2294-2301. Springer-Verlag European Radiology |
| بيانات النشر: | Springer-Verlag, 2009. |
| سنة النشر: | 2009 |
| مصطلحات موضوعية: | medicine.medical_specialty, Sensitivity and Specificity, Imaging, Three-Dimensional, Risk Factors, Internal medicine, medicine, Humans, Radiology, Nuclear Medicine and imaging, Carotid Stenosis, MDCTA, Neuroradiology, Atherosclerotic plaque, medicine.diagnostic_test, business.industry, Ultrasound, Reproducibility of Results, Interventional radiology, Vascular-Interventional, General Medicine, Middle Aged, medicine.disease, Image Enhancement, Carotid arteries, Cerebral Angiography, Stenosis, Plaque volume, medicine.anatomical_structure, Radiology Nuclear Medicine and imaging, Angiography, Cardiology, Radiographic Image Interpretation, Computer-Assisted, Female, Radiology, business, Tomography, X-Ray Computed, Cerebral angiography, Calcification, Artery |
| الوصف: | The purpose of this study was to examine the volume and the composition of atherosclerotic plaque in symptomatic carotid arteries and to investigate the relationship between these plaque features and the severity of stenosis and the presence of cardiovascular risk factors. One hundred patients with cerebrovascular symptoms underwent CT angiography. We measured plaque volume (PV) and the relative contribution of plaque components (calcifications, fibrous tissue, and lipid) in the symptomatic artery. The contribution of different components was measured as the number of voxels within defined ranges of HU values (calcification > 130 HU, fibrous tissue 60-130 HU, lipid core < 60 HU). Fifty-seven patients had atherosclerotic plaque in the symptomatic carotid artery. The severity of stenosis and PV were moderately correlated. Age and smoking were independently related to PV. Patients with hypercholesterolemia had significantly less lipid and more calcium in their plaques than patients without hypercholesterolemia. Other cardiovascular risk factors were not significantly related to PV or plaque composition. Luminal stenosis of the carotid artery partly reflects the amount of atherosclerotic carotid disease. Plaque volume and plaque composition are associated with cardiovascular risk factors. |
| تدمد: | 1432-1084 0938-7994 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12f7eeb126c0121738375d002192c79e https://pure.eur.nl/en/publications/900d3480-070b-42f8-a002-368c7b9298a7 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....12f7eeb126c0121738375d002192c79e |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 14321084 09387994 |
|---|