Protective effects of Nitraria retusa extract and its constituent isorhamnetin against amyloid β-induced cytotoxicity and amyloid β aggregation
العنوان: | Protective effects of Nitraria retusa extract and its constituent isorhamnetin against amyloid β-induced cytotoxicity and amyloid β aggregation |
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المؤلفون: | Yoko Nagumo, Takeo Usui, Feten Zar Kalai, Akihisa Iida, Hiroko Isoda, Junkyu Han |
المصدر: | Bioscience, Biotechnology, and Biochemistry. 79:1548-1551 |
بيانات النشر: | Informa UK Limited, 2015. |
سنة النشر: | 2015 |
مصطلحات موضوعية: | Amyloid, Applied Microbiology and Biotechnology, Biology, Fibril, Protein Aggregation, Pathological, Biochemistry, Cell Line, Analytical Chemistry, Magnoliopsida, chemistry.chemical_compound, Alzheimer Disease, Halophyte, Humans, Retusa, Cytotoxicity, Molecular Biology, Isorhamnetin, Cell Proliferation, Amyloid beta-Peptides, Plant Extracts, Organic Chemistry, General Medicine, biology.organism_classification, In vitro, chemistry, Nitraria retusa, Quercetin, Biotechnology |
الوصف: | Nitraria retusa is a halophyte species that is distributed in North Africa and used as a traditional medicinal plant. In this study, N. retusa ethanol extract and its constituent isorhamnetin (IRA) protected against amyloid β (Aβ)-induced cytotoxicity in human neuroblastoma SH-SY5Y cells. An in vitro Aβ aggregation assay suggested that IRA destabilizes Aβ fibrils. |
تدمد: | 1347-6947 0916-8451 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1324dec26f8d488d25689a2b08bde098 https://doi.org/10.1080/09168451.2015.1027655 |
حقوق: | OPEN |
رقم الأكسشن: | edsair.doi.dedup.....1324dec26f8d488d25689a2b08bde098 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 13476947 09168451 |
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