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Protective effects of Nitraria retusa extract and its constituent isorhamnetin against amyloid β-induced cytotoxicity and amyloid β aggregation

التفاصيل البيبلوغرافية
العنوان: Protective effects of Nitraria retusa extract and its constituent isorhamnetin against amyloid β-induced cytotoxicity and amyloid β aggregation
المؤلفون: Yoko Nagumo, Takeo Usui, Feten Zar Kalai, Akihisa Iida, Hiroko Isoda, Junkyu Han
المصدر: Bioscience, Biotechnology, and Biochemistry. 79:1548-1551
بيانات النشر: Informa UK Limited, 2015.
سنة النشر: 2015
مصطلحات موضوعية: Amyloid, Applied Microbiology and Biotechnology, Biology, Fibril, Protein Aggregation, Pathological, Biochemistry, Cell Line, Analytical Chemistry, Magnoliopsida, chemistry.chemical_compound, Alzheimer Disease, Halophyte, Humans, Retusa, Cytotoxicity, Molecular Biology, Isorhamnetin, Cell Proliferation, Amyloid beta-Peptides, Plant Extracts, Organic Chemistry, General Medicine, biology.organism_classification, In vitro, chemistry, Nitraria retusa, Quercetin, Biotechnology
الوصف: Nitraria retusa is a halophyte species that is distributed in North Africa and used as a traditional medicinal plant. In this study, N. retusa ethanol extract and its constituent isorhamnetin (IRA) protected against amyloid β (Aβ)-induced cytotoxicity in human neuroblastoma SH-SY5Y cells. An in vitro Aβ aggregation assay suggested that IRA destabilizes Aβ fibrils.
تدمد: 1347-6947
0916-8451
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1324dec26f8d488d25689a2b08bde098
https://doi.org/10.1080/09168451.2015.1027655
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....1324dec26f8d488d25689a2b08bde098
قاعدة البيانات: OpenAIRE
الوصف
تدمد:13476947
09168451