أعرض في EDS

Safety and Efficacy of a Monoclonal Antibody against Malaria in Mali

التفاصيل البيبلوغرافية
العنوان: Safety and Efficacy of a Monoclonal Antibody against Malaria in Mali
المؤلفون: Kassoum, Kayentao, Aissata, Ongoiba, Anne C, Preston, Sara A, Healy, Safiatou, Doumbo, Didier, Doumtabe, Abdrahamane, Traore, Hamadi, Traore, Adama, Djiguiba, Shanping, Li, Mary E, Peterson, Shinyi, Telscher, Azza H, Idris, Neville K, Kisalu, Kevin, Carlton, Leonid, Serebryannyy, Sandeep, Narpala, Adrian B, McDermott, Martin, Gaudinski, Siriman, Traore, Hamidou, Cisse, Mamadou, Keita, Jeff, Skinner, Zonghui, Hu, Amatigué, Zéguimé, Adama, Ouattara, M'Bouye, Doucoure, Amagana, Dolo, Abdoulaye, Djimdé, Boubacar, Traore, Robert A, Seder, Peter D, Crompton
المصدر: The New England journal of medicine. 387(20)
سنة النشر: 2022
مصطلحات موضوعية: Adult, Antimalarials, Artemether, Lumefantrine Drug Combination, Plasmodium falciparum, Headache, Humans, General Medicine, Malaria, Falciparum, Mali, Antibodies, Monoclonal, Humanized
الوصف: CIS43LS is a monoclonal antibody that was shown to protect against controlledWe conducted a phase 2 trial to assess the safety and efficacy of a single intravenous infusion of CIS43LS againstIn Part B, 330 adults underwent randomization; 110 were assigned to each trial group. The risk of moderate headache was 3.3 times as high with 40 mg of CIS43LS per kilogram as with placebo.CIS43LS was protective against
تدمد: 1533-4406
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13381ab5291d2a1c56fda511f9a85a5c
https://pubmed.ncbi.nlm.nih.gov/36317785
حقوق: CLOSED
رقم الأكسشن: edsair.doi.dedup.....13381ab5291d2a1c56fda511f9a85a5c
قاعدة البيانات: OpenAIRE
الوصف
تدمد:15334406