Selective decontamination of the digestive tract (SDD) in critically ill patients: a narrative review
| العنوان: | Selective decontamination of the digestive tract (SDD) in critically ill patients: a narrative review |
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| المؤلفون: | Brian H. Cuthbertson, Christian Brun-Buisson, Marc J. M. Bonten, Evelien A. N. Oostdijk, Bastiaan H J Wittekamp |
| المصدر: | Intensive Care Medicine |
| بيانات النشر: | Springer Berlin Heidelberg, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | musculoskeletal diseases, medicine.medical_specialty, Antibiotic resistance, Selective decontamination, Critical Illness, Review, Critical Care and Intensive Care Medicine, law.invention, law, Anesthesiology, Infection prevention, Medicine, Infection control, Humans, Intensive care medicine, Decontamination, business.industry, Critically ill, Intensive care unit, Anti-Bacterial Agents, Gastrointestinal Tract, Digestive tract, Narrative review, business |
| الوصف: | Selective decontamination of the digestive tract (SDD) is an infection prevention measure for intensive care unit (ICU) patients that was proposed more than 30 years ago, and that is currently considered standard of care in the Netherlands, but only used sporadically in ICUs in other countries. In this narrative review, we first describe the rationale of the individual components of SDD and then review the evidence base for patient-centered outcomes, where we distinguish ICUs with low prevalence of antibiotic resistance from ICUs with moderate–high prevalence of resistance. In settings with low prevalence of antibiotic resistance, SDD has been associated with improved patient outcome in three cluster-randomized studies. These benefits were not confirmed in a large international cluster-randomized study in settings with moderate-to-high prevalence of antibiotic resistance. There is no evidence that SDD increases antibiotic resistance. We end with future directions for research. Electronic supplementary material The online version of this article (10.1007/s00134-019-05883-9) contains supplementary material, which is available to authorized users. |
| اللغة: | English |
| تدمد: | 1432-1238 0342-4642 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c1537ba43176521417db17fac777fc http://europepmc.org/articles/PMC7042187 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....13c1537ba43176521417db17fac777fc |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 14321238 03424642 |
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