Multidrug resistant tuberculosis in HIV positive patients and its effect on Interleukin-2 and Interferon-γ
| العنوان: | Multidrug resistant tuberculosis in HIV positive patients and its effect on Interleukin-2 and Interferon-γ |
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| المؤلفون: | Isiyaku, Abdulahi, Hafiz, Taysir |
| المصدر: | Microbes and Infectious Diseases; Vol. 3 No. 3 (2022); 615-624 |
| بيانات النشر: | Egypts Presidential Specialized Council for Education and Scientific Research, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Materials Science (miscellaneous), Business and International Management, Cytokines, DS-TB, MDR-TB, HIV, Mycobacterium tuberculosis, Industrial and Manufacturing Engineering |
| الوصف: | Background:This is a case control study aimed to detect plasma level of interleukin-2 (IL-2) and interferon-gamma (IFN-γ) cytokines in multidrug resistant tuberculosis (MDR-TB) co-infected with human immunodeficiency virus (HIV) patients and multidrug resistant tuberculosis (MDR-TB) monoinfected patients.Methods: This study determined the differences in plasma concentrations of pro-inflammatory (IL-2 and IFN-γ) cytokines in MDR-TB co-infected with HIV patients and MDR-TB monoinfected patients. Plasma levels of IL-2 and IFN-γ were measured in 130 participants (comprising 15 MDR-TB/HIV co-infected treatment naïve patients, 15 MDR-TB/HIV co-infected treatment experienced patients, 20 MDR-TB monoinfected treatment naïve patients, 20 MDR-TB monoinfected treatment experienced patients, 20 drug susceptible tuberculosis (DS-TB) co-infected with HIV treatment experienced patients and 40 apparently healthy control groups) using enzyme-linked immunosorbant assay (ELISA).Results: Shows that the mean plasma level of IL-2 (210.02 ± 59.27pg/ml) measured in MDR-TB co-infected with HIV treatment-naïve patients (group 1a) was significantly (p < /em> |
| وصف الملف: | application/pdf |
| تدمد: | 2682-4140 2682-4132 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1485924586af402aca0601eae28d4bd3 https://doi.org/10.21608/mid.2022.139946.1317 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....1485924586af402aca0601eae28d4bd3 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 26824140 26824132 |
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