United States Medical Practice Summary
| العنوان: | United States Medical Practice Summary |
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| المؤلفون: | Robert J. Weber, Carl A. Sirio, Susan J. Skledar, Nicole T. Ansani, Thomas Smitherman, Nathalie K. Zgheib, Robert A. Branch, Bethany A. Fedutes-Henderson |
| المصدر: | American Journal of Medical Quality. 21:246-254 |
| بيانات النشر: | Ovid Technologies (Wolters Kluwer Health), 2006. |
| سنة النشر: | 2006 |
| مصطلحات موضوعية: | musculoskeletal diseases, medicine.medical_specialty, Alternative medicine, MEDLINE, Pharmacy, Off-label use, 03 medical and health sciences, 0302 clinical medicine, Drug Therapy, Nursing, Practice Management, Medical, Humans, Medicine, 030212 general & internal medicine, Drug Labeling, Protocol (science), Medical education, Medication use, business.industry, 030503 health policy & services, Health Policy, Medical practice, United States, Data sharing, Cross-Sectional Studies, Pharmaceutical Preparations, Pharmaceutical Services, 0305 other medical science, business |
| الوصف: | Data are limited regarding how academic medical centers (AMCs) deal with medication use that represents a departure from product labeling; has reasonable rationale for use, but insufficient evidence to allay safety, efficacy, and cost-effectiveness concerns; yet is not clinical research (defined as innovative off-label medication use). This report describes national trends in management of innovative off-label medication use. A cross-sectional survey of US AMCs was conducted. Survey questionnaires were directed to drug information centers or pharmacy directors. Of 469 AMCs contacted, 104 responded (22%). Fifty-nine AMCs identified innovative off-label use as a challenge. Only 18 AMCs developed strategies to address this issue: 12 requiring initial reviews and 8 requiring clinical monitoring. Sixty-five AMCs indicated interest in data sharing of clinical outcomes for innovative off-label protocol(s). Innovative off-label medication use is a widely recognized challenge; however, few prospectively active AMC responses exist. The authors suggest development of systematic structured approaches within and across AMCs. |
| تدمد: | 1555-824X 1062-8606 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e424283ea0712c81fb7f37e932f9b4 https://doi.org/10.1177/1062860606288346 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....14e424283ea0712c81fb7f37e932f9b4 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1555824X 10628606 |
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