Dynamic SOFA score assessments to predict outcomes after acute admission of octogenarians to the intensive care unit
| العنوان: | Dynamic SOFA score assessments to predict outcomes after acute admission of octogenarians to the intensive care unit |
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| المؤلفون: | Thibaut Trouve-Buisson, Lydiane Agier, Emmanuelle Loyrion, Gaëtan Gavazzi, Jean-François Payen, Jean-Luc Bosson, Carole Schwebel |
| المصدر: | PLoS ONE, Vol 16, Iss 8, p e0253077 (2021) PLoS ONE PLoS ONE, Vol 16, Iss 8 (2021) |
| بيانات النشر: | Public Library of Science (PLoS), 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Male, Pulmonology, Organ Dysfunction Scores, Health Care Providers, law.invention, 0302 clinical medicine, law, Activities of Daily Living, Medicine and Health Sciences, Hospital Mortality, Prospective Studies, Medical Personnel, 030212 general & internal medicine, Aged, 80 and over, Geriatrics, Multidisciplinary, Frailty, Mortality rate, Hazard ratio, Intensive care unit, Hospitals, Hospitalization, Intensive Care Units, Professions, Medicine, Female, SOFA score, Research Article, Cohort study, medicine.medical_specialty, Death Rates, Critical Illness, Frail Elderly, Science, Surgical and Invasive Medical Procedures, 03 medical and health sciences, Population Metrics, Physicians, medicine, Humans, Population Biology, Proportional hazards model, business.industry, Biology and Life Sciences, 030208 emergency & critical care medicine, Confidence interval, Health Care, Health Care Facilities, People and Places, Emergency medicine, Quality of Life, Population Groupings, business |
| الوصف: | Background Identifying which octogenarians could benefit most from continuing critical care is challenging. We aimed to see if responses to therapies using the sequential organ failure assessment (SOFA) score on day 4 after unplanned admission to the intensive care unit (ICU) could be associated with short-term mortality. Methods In this prospective observational cohort study, data from 4 ICUs in a University Hospital included SOFA scores on admission and day 4, along with preadmission measurements of frailty, comorbidities, nutritional status and number of medications. Outcome measures included mortality and loss of autonomy on day 90 after admission. Results Eighty-seven critically ill patients aged 80 years or older with preadmission functional independence and no missing SOFA score data on day 4 were studied (primary analyses). The mortality rate on day 90 was 30%. In a univariate Cox model, the SOFA score on day 4 was significantly associated with mortality rate: hazard ratio = 1.18 per one-point increase, 95% confidence interval (CI), 1.08 to 1.28 (p Conclusion Measuring SOFA score on day 4 and preadmission frailty could help predict mortality and loss of autonomy on day 90 in octogenarians after their acute admission to the ICU. |
| تدمد: | 1932-6203 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::160ffb77e51b41d5bb11bad94073cfdd https://doi.org/10.1371/journal.pone.0253077 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....160ffb77e51b41d5bb11bad94073cfdd |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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