Micronutrient Deficiencies Following Minimally Invasive Esophagectomy for Cancer
| العنوان: | Micronutrient Deficiencies Following Minimally Invasive Esophagectomy for Cancer |
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| المؤلفون: | Misha D. P. Luyer, Jeroen E. H. Ponten, Henricus J. B. Janssen, Grard A. P. Nieuwenhuijzen, Laura F C Fransen |
| المصدر: | Nutrients Volume 12 Issue 3 Nutrients, Vol 12, Iss 3, p 778 (2020) |
| بيانات النشر: | Multidisciplinary Digital Publishing Institute, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Micronutrient deficiency, Time Factors, Esophageal Neoplasms, Anemia, medicine.medical_treatment, Methylmalonic acid, Nutritional Status, lcsh:TX341-641, micronutrient deficiencies, Gastroenterology, Article, Cohort Studies, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Postoperative Complications, Interquartile range, Internal medicine, medicine, Humans, Vitamin B12, Micronutrients, Postoperative Period, esophageal cancer, Aged, Randomized Controlled Trials as Topic, Nutrition and Dietetics, business.industry, Malnutrition, Esophageal cancer, Middle Aged, medicine.disease, Micronutrient, chemistry, Esophagectomy, 030220 oncology & carcinogenesis, Dietary Supplements, esophagectomy, 030211 gastroenterology & hepatology, Female, business, vitamin deficiencies, lcsh:Nutrition. Foods and food supply, Food Science |
| الوصف: | Over the past decades, survival rates for patients with resectable esophageal cancer have improved significantly. Consequently, the sequelae of having a gastric conduit, such as development of micronutrient deficiencies, become increasingly apparent. This study investigated postoperative micronutrient trends in the follow-up of patients following a minimally invasive esophagectomy (MIE) for cancer. Patients were included if they had at least one postoperative evaluation of iron, ferritin, vitamins B1, B6, B12, D, folate or methylmalonic acid. Data were available in 83 of 95 patients. Of these, 78.3% (65/83) had at least one and 37.3% (31/83) had more than one micronutrient deficiency at a median of 6.1 months (interquartile range (IQR) 5.4&ndash 7.5) of follow-up. Similar to the results found in previous studies, most common deficiencies identified were: iron, vitamin B12 and vitamin D. In addition, folate deficiency and anemia were detected in a substantial amount of patients in this cohort. At 24.8 months (IQR 19.4&ndash 33.1) of follow-up, micronutrient deficiencies were still common, however, most deficiencies normalized following supplementation on indication. In conclusion, patients undergoing a MIE are at risk of developing micronutrient deficiencies as early as 6 up to 24 months after surgery and should therefore be routinely checked and supplemented when needed. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2072-6643 |
| DOI: | 10.3390/nu12030778 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16f3fc4283ebb7cd68c2abc354a54644 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....16f3fc4283ebb7cd68c2abc354a54644 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20726643 |
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| DOI: | 10.3390/nu12030778 |