Effects of changes in end-tidal carbon dioxide tension on oral tissue blood flow and tissue oxygen tension during remifentanil infusion in rabbits
| العنوان: | Effects of changes in end-tidal carbon dioxide tension on oral tissue blood flow and tissue oxygen tension during remifentanil infusion in rabbits |
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| المؤلفون: | Yui Akiike, Nobuyuki Matsuura, Ai Yamazaki, Kyotaro Koshika, Tatsuya Ichinohe, Masataka Kasahara |
| المصدر: | Journal of Anesthesia. 36:52-57 |
| بيانات النشر: | Springer Science and Business Media LLC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Male, Methyl Ethers, Mean arterial pressure, Remifentanil, Blood Pressure, Sevoflurane, Masseter muscle, Tongue, Heart rate, medicine, Animals, business.industry, Blood flow, Carbon Dioxide, Oxygen, Anesthesiology and Pain Medicine, medicine.anatomical_structure, Blood pressure, Regional Blood Flow, Anesthesia, Rabbits, Bone marrow, business, Anesthetics, Intravenous, circulatory and respiratory physiology, medicine.drug |
| الوصف: | The aim of this study was to investigate the effects of end-tidal carbon dioxide tension (ETCO2) changes during remifentanil infusion on mandibular bone marrow tissue blood flow (BBF), masseter muscle tissue blood flow (MBF), mandibular bone marrow tissue oxygen tension (PbO2) and masseter muscle tissue oxygen tension (PmO2) in rabbits. Ten male tracheotomized Japan White rabbits were anesthetized and ventilated with sevoflurane. ETCO2 was adjusted to 30 mmHg. After baseline measurement, CO2 was added to the inhaled air, and ETCO2 was increased to 40 and 60 mmHg. Heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), BBF, MBF, PbO2, and PmO2 were recorded with and without remifentanil infusion at 0.4 µg/kg/min. Two-way repeated measures analysis of variance showed no interaction between ETCO2 and remifentanil in all variables. Remifentanil infusion produced decreases in HR, SBP, MAP, BBF and MBF compared with those without remifentanil infusion, while it did not affect DBP, PbO2 and PmO2. Elevation of ETCO2 from 30 to 60 mmHg produced decreases in HR and MBF, and increases in SBP, DBP, MAP and BBF, while it did not affect PbO2 and PmO2. PbO2 and PmO2 remained unchanged despite changes in BBF and MBF during ETCO2 change with or without remifentanil infusion. |
| تدمد: | 1438-8359 0913-8668 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17166f1861fbcdc0f39ad0c5bf8fe1d4 https://doi.org/10.1007/s00540-021-03006-7 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....17166f1861fbcdc0f39ad0c5bf8fe1d4 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 14388359 09138668 |
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