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Preoperative risk stratification of lymph node metastasis for non-functional pancreatic neuroendocrine neoplasm: An international dual-institutional study

التفاصيل البيبلوغرافية
العنوان: Preoperative risk stratification of lymph node metastasis for non-functional pancreatic neuroendocrine neoplasm: An international dual-institutional study
المؤلفون: Etsuro Hatano, Emily K. Bergsland, Grace E. Kim, Bryan K. Le, Eric K. Nakakura, Asahi Sato, Thomas A. Hope, Kazuyuki Nagai, Toshihiko Masui, Kyoichi Takaori, Yosuke Kasai, Takayuki Anazawa, Yuichiro Uchida, Kenzo Nakano, Akitada Yogo, Shinji Uemoto, Julia Whitman
المصدر: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]. 22(1)
سنة النشر: 2021
مصطلحات موضوعية: Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Lymph node metastasis, Logistic regression, Gastroenterology, Risk Assessment, California, Japan, Predictive Value of Tests, Risk Factors, Internal medicine, medicine, Humans, Neoplasm Invasiveness, Aged, Neoplasm Staging, Retrospective Studies, Pancreatic duct, Hepatology, business.industry, Odds ratio, Middle Aged, Confidence interval, Pancreatic Neuroendocrine Neoplasm, Pancreatic Neoplasms, medicine.anatomical_structure, Lymphatic Metastasis, Lymph Node Excision, Lymphadenectomy, Female, Lymph, Lymph Nodes, business
الوصف: BACKGROUND /Objectives: Although the presence of lymph node metastasis (LNM) defines malignant potential, preoperative prediction of LNM has not been established for non-functional pancreatic neuroendocrine neoplasm (NF-PNEN). We sought to develop a prediction system using only preoperatively available factors that would stratify the risk of LNM for NF-PNEN. METHODS We retrospectively reviewed patients who underwent R0/1 resection of NF-PNEN at Kyoto University (2007-2019) and the University of California, San Francisco (2010-2019). Risk stratification of LNM was developed using preoperative factors by the logistic regression analysis. Long-term outcomes were compared across the risk groups. RESULTS A total of 131 patients were included in this study. Lymph nodes were pathologically examined in 116 patients, 23 (20%) of whom had LNM. Radiological tumor size [1.5-3.5 cm (odds ratio: 13.5, 95% confidence interval: 1.77-398) and >3.5 cm (72.4, 9.06-2257) against ≤1.5 cm]
تدمد: 1424-3911
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e286bd1747801665cb476b31a08839
https://pubmed.ncbi.nlm.nih.gov/34736838
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....18e286bd1747801665cb476b31a08839
قاعدة البيانات: OpenAIRE
الوصف
تدمد:14243911