Restoring Endogenous Repair Mechanisms to Heal Chronic Wounds with a Multifunctional Wound Dressing
| العنوان: | Restoring Endogenous Repair Mechanisms to Heal Chronic Wounds with a Multifunctional Wound Dressing |
|---|---|
| المؤلفون: | Rahimeh B. Atashgah, Vahid Serpooshan, Hojatollah Vali, Doris L. LaRock, Rouzbeh Sarrafi, Holger Schönherr, Carmen Alvarez-Lorenzo, Andrea S. Theus, Mehdi Akbarzadeh, Mohammad Raoufi, Lisa J. Gould, Mohammad-Amin Abdollahifar, Seyed Nasser Ostad, Pablo Taboada, Morteza Mahmoudi, Ki-Bum Lee, Amir Ghasemi, Hossein Nejadnik, Shahriar Sharifi, Steven Zanganeh, Miguel Cuerva, Christopher N. LaRock, Baltazar Lea, Alieh Abdollahi |
| المصدر: | Molecular Pharmaceutics. 18:3171-3180 |
| بيانات النشر: | American Chemical Society (ACS), 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Male, Staphylococcus aureus, Follistatin-Related Proteins, Cell Survival, Angiogenesis, Surgical Wound, Anti-Inflammatory Agents, Nanofibers, Pharmaceutical Science, Biocompatible Materials, Endogeny, Inflammation, Diabetes Mellitus, Experimental, Mice, Biopolymers, Materials Testing, Drug Discovery, Animals, HaCaT Cells, Humans, Medicine, Rats, Wistar, Annexin A1, Wound Healing, integumentary system, business.industry, Biofilm, 3T3 Cells, Staphylococcal Infections, Bandages, Rats, Cell biology, Treatment Outcome, Wound dressing, Wound Infection, Molecular Medicine, Magnetic Iron Oxide Nanoparticles, medicine.symptom, Peptides, business, Wound healing |
| الوصف: | Current treatment of chronic wounds has been critically limited by various factors, including bacterial infection, biofilm formation, impaired angiogenesis, and prolonged inflammation. Addressing these challenges, we developed a multifunctional wound dressing-based three-pronged approach for accelerating wound healing. The multifunctional wound dressing, composed of nanofibers, functional nanoparticles, natural biopolymers, and selected protein and peptide, can target multiple endogenous repair mechanisms and represents a promising alternative to current wound healing products. |
| تدمد: | 1543-8392 1543-8384 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a7af072610db6532d3bf15e75f2a521 https://doi.org/10.1021/acs.molpharmaceut.1c00400 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....1a7af072610db6532d3bf15e75f2a521 |
| قاعدة البيانات: | OpenAIRE |
Find this issue from the American Chemical Society | تدمد: | 15438392 15438384 |
|---|