Oral health in patients scheduled for hematopoietic stem cell transplantation in the Orastem study
| العنوان: | Oral health in patients scheduled for hematopoietic stem cell transplantation in the Orastem study |
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| المؤلفون: | Kristina Skallsjö, Inger von Bültzingslöwen, Bengt Hasséus, Jan-Erik Johansson, Jenny Öhman, Judith E. Raber-Durlacher, Marie-Charlotte D. N. J. M. Huysmans, Alexa M. G. A. Laheij, Stephanie J. M. van Leeuwen, Allan J. Hovan, Karin Garming Legert, Hieu M. Nguyen, Philip J. Turk, Frederik R. Rozema, Nicole M. A. Blijlevens, Michael T. Brennan |
| المساهمون: | Oral and Maxillofacial Surgery, Oral Medicine, Maxillofacial Surgery (AMC + VUmc), Oral and Maxillofacial Surgery / Oral Pathology |
| المصدر: | Skallsjö, K, von Bültzingslöwen, I, Hasséus, B, Johansson, J E, Öhman, J, Raber-Durlacher, J E, Huysmans, M C D N J M, Laheij, A M G A, van Leeuwen, S J M, Hovan, A J, Legert, K G, Nguyen, H M, Turk, P J, Rozema, F R, Blijlevens, N M A & Brennan, M T 2023, ' Oral health in patients scheduled for hematopoietic stem cell transplantation in the Orastem study ', PLoS ONE, vol. 18, no. 5, e0285615, pp. 1-18 . https://doi.org/10.1371/journal.pone.0285615 PLoS One, 18 PLoS One, 18, 5 PLoS ONE, 18(5 May):e0285615. Public Library of Science PLoS ONE, 18(5):e0285615, 1-18. Public Library of Science Skallsjö, K, von Bültzingslöwen, I, Hasséus, B, Johansson, J-E, Öhman, J, Raber-Durlacher, J E, Huysmans, M-C D N J M, Laheij, A M G A, van Leeuwen, S J M, Hovan, A J, Legert, K G, Nguyen, H M, Turk, P J, Rozema, F R, Blijlevens, N M A & Brennan, M T 2023, ' Oral health in patients scheduled for hematopoietic stem cell transplantation in the Orastem study ', PLoS ONE, vol. 18, no. 5 May, e0285615 . https://doi.org/10.1371/journal.pone.0285615 |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10], All institutes and research themes of the Radboud University Medical Center, Multidisciplinary, SDG 3 - Good Health and Well-being, Rare cancers Radboud Institute for Health Sciences [Radboudumc 9] |
| الوصف: | Contains fulltext : 292890.pdf (Publisher’s version ) (Open Access) Despite advances in transplant medicine, prevalence of complications after hematopoietic stem cell transplantation (HSCT) remains high. The impact of pre-HSCT oral health factors on the incidence and severity of complications post-HSCT is poorly understood. The aim of this prospective, observational study was to analyze oral health in patients planned for HSCT. Patients ≥18 years requiring HSCT were included from five sites between 2011-2018. General health, oral findings and patient-reported symptoms were registered in 272 patients. Oral symptoms around disease onset were reported by 43 patients (15.9%) and 153 patients (58.8%) reported oral complications during previous chemotherapy. One third of patients experienced oral symptoms at the oral examination before conditioning regimen and HSCT. In total, 124 (46.1%) patients had dental caries, 63 (29.0%) had ≥one tooth with deep periodontal pockets, 147 (75.0%) had ≥one tooth with bleeding on probing. Apical periodontitis was observed in almost 1/4 and partially impacted teeth in 17 (6.3%) patients. Oral mucosal lesions were observed in 84 patients (30.9%). A total of 45 (17.4%) of 259 patients had at least one acute issue to be managed prior to HSCT. In conclusion, oral symptoms and manifestations of oral disease were prevalent in patients planned for HSCT. The extent of oral and acute dental diseases calls for general oral screening of patients pre-HSCT. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1932-6203 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a8e73f03e5ee83becd91329218168f5 https://research.vu.nl/en/publications/7705dadd-7463-44f6-a957-01739e1e532d |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....1a8e73f03e5ee83becd91329218168f5 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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