Response Factors Enable Rapid Quantitative 2D NMR Analysis in Catalytic Biomass Conversion to Renewable Chemicals
| العنوان: | Response Factors Enable Rapid Quantitative 2D NMR Analysis in Catalytic Biomass Conversion to Renewable Chemicals |
|---|---|
| المؤلفون: | Samuel Gilbert Elliot, Anders Riisager, Esben Taarning, Sebastian Meier, Irene Tosi |
| المصدر: | Elliot, S G, Tosi, I, Riisager, A, Taarning, E & Meier, S 2019, ' Response Factors Enable Rapid Quantitative 2D NMR Analysis in Catalytic Biomass Conversion to Renewable Chemicals ', Topics in Catalysis, vol. 62, no. 7-11, pp. 580-598 . https://doi.org/10.1007/s11244-019-01131-y |
| بيانات النشر: | Springer Science and Business Media LLC, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Detection limit, Response factor, 010405 organic chemistry, Chemistry, Biomass, General Chemistry, 010402 general chemistry, qNMR, 01 natural sciences, Catalysis, 0104 chemical sciences, Reference standard, Atom economy, SDG 7 - Affordable and Clean Energy, Biochemical engineering, Biorefining, Quantitative analysis, Quantitative analysis (chemistry), Two-dimensional nuclear magnetic resonance spectroscopy, Isomerization |
| الوصف: | Carbohydrate conversion offers access to a variety of chemicals with diverse functionalities. An accurate analysis of the multiple products in post-reaction material is indispensable for enabling good atom economy in biorefining. A certain need for reconsidering current analytical approaches to chemocatalytic biomass conversion is witnessed by the often poor carbon balances that are reported for carbohydrate conversion processes. Carbohydrate conversion usually includes isomerization and/or dehydration, therefore analytical approaches that are suitable for the distinction and concurrent quantification of isomers are desirable for developing sustainable processes towards known and new chemicals. Quantitative 1D NMR spectroscopy can be used to determine absolute concentrations in the absence of purified reference compounds and can thereafter be used to obtain response factors in other analytical methods resolving the compounds of interest. Here, we show that this approach is applicable for obtaining response factors relative to an internal standard for rapid, highly resolved 2D NMR spectra at natural isotopic abundance. Following calibration, this approach provides a limit of quantification in the order of 0.8 mM within an experiment time of a few minutes. The approach is particularly beneficial for the quantification of compounds at low concentrations, for instance in initial rate experiments, and for the quantification of low populated reaction intermediates. |
| وصف الملف: | application/pdf |
| تدمد: | 1572-9028 1022-5528 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1acc9fc7924dbf0f76eef8a01ccc0c17 https://doi.org/10.1007/s11244-019-01131-y |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....1acc9fc7924dbf0f76eef8a01ccc0c17 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 15729028 10225528 |
|---|