Apathy, not depressive symptoms, as a predictor of semantic and phonemic fluency task performance in stroke and transient ischemic attack
| العنوان: | Apathy, not depressive symptoms, as a predictor of semantic and phonemic fluency task performance in stroke and transient ischemic attack |
|---|---|
| المؤلفون: | Keera N. Fishman, Demetrios J. Sahlas, Krista L. Lanctôt, Megan L Cayley, Andrea R. Ashbaugh, Nathan Herrmann, Richard H. Swartz, Karen Lien, Michelle N. Sicard, Brian J. Murray |
| المصدر: | Journal of Clinical and Experimental Neuropsychology. 40:449-461 |
| بيانات النشر: | Informa UK Limited, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Adult, Male, Adolescent, Apathy, Neuropsychological Tests, 050105 experimental psychology, Developmental psychology, Young Adult, 03 medical and health sciences, Fluency, 0302 clinical medicine, Predictive Value of Tests, medicine, Humans, 0501 psychology and cognitive sciences, Young adult, Stroke, Depression (differential diagnoses), Aged, Aged, 80 and over, Depression, Verbal Behavior, 05 social sciences, Neuropsychology, Reproducibility of Results, Cognition, Middle Aged, Center for Epidemiologic Studies Depression Scale, medicine.disease, Semantics, Clinical Psychology, Cross-Sectional Studies, Neuropsychology and Physiological Psychology, Neurology, Ischemic Attack, Transient, Female, Neurology (clinical), medicine.symptom, Psychology, 030217 neurology & neurosurgery, Clinical psychology |
| الوصف: | This study examined the relationship between apathy and cognition in patients with cerebrovascular disease. Apathy may result from damage to frontal subcortical circuits causing dysexecutive syndromes, but apathy is also related to depression. We assessed the ability of apathy to predict phonemic fluency and semantic fluency performance after controlling for depressive symptoms in 282 individuals with stroke and/or transient ischemic attack.Participants (N = 282) completed the Phonemic Fluency Test, Semantic Fluency Test, Center for Epidemiologic Studies Depression Scale, and Apathy Evaluation Scale. A cross-sectional correlational design was utilized.Using hierarchical linear regressions, apathy scores significantly predicted semantic fluency performance (β = -.159, p = .020), but not phonemic fluency performance (β = -.112, p = .129) after scaling scores by age and years of education and controlling for depressive symptoms. Depressive symptoms entered into the first step of both hierarchical linear regressions did not predict semantic fluency (β = -.035, p = .554) or phonemic fluency (β = -.081, p = .173). Apathy and depressive symptoms were moderately correlated, r(280) = .58, p .001.The results of this study are consistent with research supporting a differentiation between phonemic and semantic fluency tasks, whereby phonemic fluency tasks primarily involve frontal regions, and semantic fluency tasks involve recruitment of more extended networks. The results also highlight a distinction between apathy and depressive symptoms and suggest that apathy may be a more reliable predictor of cognitive deficits than measures of mood in individuals with cerebrovascular disease. Apathy may also be more related to cognition due to overlapping motivational and cognitive frontal subcortical circuitry. Future research should explore whether treatments for apathy could be a novel target for improving cognitive outcomes after stroke. |
| تدمد: | 1744-411X 1380-3395 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b203b5773dcf11f12e56086bc39956d https://doi.org/10.1080/13803395.2017.1371282 |
| رقم الأكسشن: | edsair.doi.dedup.....1b203b5773dcf11f12e56086bc39956d |
| قاعدة البيانات: | OpenAIRE |
PDF full text from Publisher | تدمد: | 1744411X 13803395 |
|---|