Genomic analysis of Enterococcus durans LAB18S, a potential probiotic strain isolated from cheese

التفاصيل البيبلوغرافية
العنوان: Genomic analysis of Enterococcus durans LAB18S, a potential probiotic strain isolated from cheese
المؤلفون: Carolina Baldisserotto Comerlato, Janira Prichula, Franciele Maboni Siqueira, Ana Carolina Ritter, Ana Paula Muterle Varela, Fabiana Quoos Mayer, Adriano Brandelli
المصدر: Genetics and Molecular Biology, Volume: 45, Issue: 1, Article number: e20210201, Published: 25 FEB 2022
Genetics and Molecular Biology v.45 n.1 2022
Genetics and Molecular Biology
Sociedade Brasileira de Genética (SBG)
instacron:SBG
Repositório Institucional da UFRGS
Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
بيانات النشر: Sociedade Brasileira de Genética, 2022.
سنة النشر: 2022
مصطلحات موضوعية: Enterococcus durans, Sequência genômica, prebiotic, Genetics, selenoproteins, probiotc, Probiótico, Selenoproteínas, Molecular Biology, genome, Enterococcus
الوصف: Gut microbiota exerts a fundamental role in human health and increased evidence supports the beneficial role of probiotic microorganisms in the maintenance of intestinal health. Enterococcus durans LAB18S was previously isolated from soft cheese and showed some desirable in vitro probiotic properties, for that reason its genome was sequenced and evaluated for genes that can be relevant for probiotic activity and are involved in selenium metabolism. Genome sequencing was performed using the Illumina MiSeq System. A variety of genes potentially associated with probiotic properties, including adhesion capability, viability at low pH, bile salt resistance, antimicrobial activity, and utilization of prebiotic fructooligosaccharides (FOS) were identified. The strain showed tolerance to acid pH and bile salts, exhibited antimicrobial activity and thrived on prebiotic oligosaccharides. Six genes involved in selenium metabolism were predicted. Analysis of the SECIS element showed twelve known selenoprotein candidates. E. durans LAB18S was the only food isolate showing absence of plasmids, virulence and antimicrobial resistance genes, when compared with other 30 E. durans genomes. The results of this study provide evidence supporting the potential of E. durans LAB18S as alternative for probiotic formulations.
وصف الملف: text/html; application/pdf
اللغة: English
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b6d6208ea14df4f0d2bcfc3aa6d911e
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572022000100403&lng=en&tlng=en
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....1b6d6208ea14df4f0d2bcfc3aa6d911e
قاعدة البيانات: OpenAIRE