Concentrations of cyanide in blood samples of corpses after smoke inhalation of varying origin

التفاصيل البيبلوغرافية
العنوان: Concentrations of cyanide in blood samples of corpses after smoke inhalation of varying origin
المؤلفون: W. Keil, Gabriele Roider, Simone Stoll
المصدر: International Journal of Legal Medicine. 131:123-129
بيانات النشر: Springer Science and Business Media LLC, 2016.
سنة النشر: 2016
مصطلحات موضوعية: Adult, Male, Adolescent, Cyanide, Smoke inhalation, Hydrogen cyanide, Poison control, Fires, Pathology and Forensic Medicine, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, Confined Spaces, 0302 clinical medicine, Blood concentration, Humans, Medicine, 030216 legal & forensic medicine, Child, Aged, Aged, 80 and over, Smoke, Carbon Monoxide, Cyanides, business.industry, Environmental engineering, 030208 emergency & critical care medicine, Middle Aged, Smoke Inhalation Injury, medicine.disease, Carboxyhemoglobin, Pharmaceutical Preparations, chemistry, Environmental chemistry, Blood Alcohol Content, Female, business, Pharmaceutical Substances
الوصف: Cyanide (CN) blood concentration is hardly considered during routine when evaluating smoke gas intoxications and fire victims, although some inflammable materials release a considerable amount of hydrogen cyanide. CN can be significant for the capacity to act and can in the end even be the cause of death. Systematic data concerning the influence of different fire conditions, especially those of various inflammable materials, on the CN-blood concentration of deceased persons do not exist. This study measured the CN level in 92 blood samples of corpses. All persons concerned were found dead in connection with fires and/or smoke gases. At the same time, the carboxyhemoglobin (COHb) level was determined, and the corpses were examined to detect pharmaceutical substances, alcohol and drugs. Furthermore, we analysed autopsy findings and the investigation files to determine the inflammable materials and other circumstances of the fires. Due to the inflammable materials, the highest concentration of CN in the victims was found after enclosed-space fires (n = 45) and after motor-vehicle fires (n = 8). The CN levels in these two groups (n = 53) were in 47 % of the cases toxic and in 13 % of the cases lethal. In victims of charcoal grills (n = 17) and exhaust gases (n = 6), no or only traces of CN were found. Only one case of the self-immolations (n = 12) displayed a toxic CN level. The results show that CN can have considerable significance when evaluating action ability and cause of death with enclosed-space fires and with motor-vehicle fires.
تدمد: 1437-1596
0937-9827
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc4fc8e157c45b2261e81b6765b03f4
https://doi.org/10.1007/s00414-016-1426-0
حقوق: CLOSED
رقم الأكسشن: edsair.doi.dedup.....1bc4fc8e157c45b2261e81b6765b03f4
قاعدة البيانات: OpenAIRE