MitraClip After Failed Surgical Mitral Valve Repair—An International Multicenter Study
| العنوان: | MitraClip After Failed Surgical Mitral Valve Repair—An International Multicenter Study |
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| المؤلفون: | Theresa Wißt, Matteo Saccocci, Christian Frerker, Rodrigo Estévez-Loureiro, Shingo Kuwata, Michael J. Reardon, David Scott Lim, Roberto Nerla, Victoria Delgado, Fausto Castriota, Peter de Jaegere, Damiano Regazzoli, Ross F. Garberich, Danny Dvir, Daniel Braun, Gian Paolo Ussia, Maurizio Taramasso, Stephen H. Little, Francesco Maisano, Azeem Latib, Carmelo Grasso, Paul Sorajja, Zouhair Rahhab, Eleonora Avenatti, Alper Öner, Nicolas M. Van Mieghem, Hüseyin Ince, Corrado Tamburino, Jörg Hausleiter, Hind Alosaimi, Nicolo Piazza, Jeroen J. Bax |
| المساهمون: | Cardiology |
| المصدر: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease, 10(7). WILEY Journal of the American Heart Association, 10(7):e019236. Wiley-Blackwell Publishing Ltd |
| بيانات النشر: | John Wiley and Sons Inc., 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, Mitral valve repair, Mitral regurgitation, business.industry, MitraClip, medicine.medical_treatment, recurrent mitral regurgitation, 030204 cardiovascular system & hematology, surgical mitral valve repair, Interventional Cardiology, Surgery, 03 medical and health sciences, 0302 clinical medicine, Multicenter study, Valvular Heart Disease, medicine, 030212 general & internal medicine, Cardiology and Cardiovascular Medicine, business, Mitral valve surgery, Original Research |
| الوصف: | Background Recurrence of mitral regurgitation (MR) after surgical mitral valve repair (SMVR) varies and may require reoperation. Redo mitral valve surgery can be technically challenging and is associated with increased risk of mortality and morbidity. We aimed to assess the feasibility and safety of MitraClip as a treatment strategy after failed SMVR and identify procedure modifications to overcome technical challenges. Methods and Results This international multicenter observational retrospective study collected information for all patients from 16 high‐volume hospitals who were treated with MitraClip after failed SMVR from October 29, 2009, until August 1, 2017. Data were anonymously collected. Technical and device success were recorded per modified Mitral Valve Academic Research Consortium criteria. Overall, 104 consecutive patients were included. Median Society of Thoracic Surgeons score was 4.5% and median age was 73 years. At baseline, the majority of patients (82%) were in New York Heart Association class ≥III and MR was moderate or higher in 86% of patients. The cause of MR pre‐SMVR was degenerative in 50%, functional in 35%, mixed in 8%, and missing/unknown in 8% of patients. The median time between SMVR and MitraClip was 5.3 (1.9–9.7) years. Technical and device success were 90% and 89%, respectively. Additional/modified imaging was applied in 21% of cases. An MR reduction of ≥1 grade was achieved in 94% of patients and residual MR was moderate or less in 90% of patients. In‐hospital all‐cause mortality was 2%, and 86% of patients were in New York Heart Association class ≤II. Conclusions MitraClip is a safe and less invasive treatment option for patients with recurrent MR after failed SMVR. Additional/modified imaging may help overcome technical challenges during leaflet grasping. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2047-9980 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c7ace2f9b77b7a5a9cc515db40a2da9 http://europepmc.org/articles/PMC8174343 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....1c7ace2f9b77b7a5a9cc515db40a2da9 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20479980 |
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