Acute Kidney Injury and COVID-19: A Picture from an Intensive Care Unit
| العنوان: | Acute Kidney Injury and COVID-19: A Picture from an Intensive Care Unit |
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| المؤلفون: | Valentina Pistolesi, Giancarlo Ceccarelli, Franco Ruberto, Santo Morabito, Francesco Pugliese, Chiara Manganelli, Francesco Alessandri |
| المصدر: | Blood Purification. 50:767-771 |
| بيانات النشر: | S. Karger AG, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Male, Continuous renal replacement therapy, Renal failure, medicine.medical_specialty, Critical Illness, medicine.medical_treatment, Renal function, urologic and male genital diseases, law.invention, Acute kidney injury, Coronavirus disease 2019, Renal Dialysis, Oliguria, law, medicine, Humans, Renal replacement therapy, Dialysis, Aged, Aged, 80 and over, SARS-CoV-2, business.industry, COVID-19, Hematology, General Medicine, Middle Aged, medicine.disease, Intensive care unit, Intensive Care Units, Respiratory failure, Nephrology, Emergency medicine, Female, medicine.symptom, business, Kidney disease |
| الوصف: | Introduction: Acute kidney injury (AKI) is a frequent complication in coronavirus disease 2019 (COVID-19) patients admitted to intensive care unit (ICU) for severe respiratory failure. The aim is to evaluate the rate of AKI, defined according to Kidney Disease: Improving Global Outcome guidelines, in a series of critical COVID-19 patients admitted to the ICU of a single tertiary teaching hospital. Methods: From April to May 2020, all consecutive critically ill COVID-19 patients admitted to the ICU who did not meet exclusion criteria (length of ICU stay Results: Sixty-one patients were included in the analysis. AKI was observed in 35/61 patients (57.4%): 25/35 episodes (71.4%) were observed within the first 7 days. AKI was classified as follows: 17.1% stage 1, 25.7% stage 2, and 57.2% stage 3. Fourteen out of 20 stage-3 patients required continuous renal replacement therapy (CRRT), mostly related to persistent oliguria. The overall ICU mortality was 68.9%, and it was higher in patients developing AKI if compared to no-AKI patients (p = 0.006). Renal function recovery of any grade was observed in 14 out of 35 AKI patients (40%). Among patients undergoing CRRT, 13 patients were still dialysis dependent at the time of death. Conclusion: In critical COVID-19 patients, ICU mortality is particularly high, especially in patients developing AKI. An accurate monitoring of renal function in early phases of respiratory failure should be ensured in order to timely apply any strategy aimed at limiting renal complications during ICU stay. |
| تدمد: | 1421-9735 0253-5068 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c99143b297963a006ad45ad617253d6 https://doi.org/10.1159/000513153 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....1c99143b297963a006ad45ad617253d6 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14219735 02535068 |
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