التفاصيل البيبلوغرافية
العنوان:
Protective effect of Alstonia scholaris Linn. R. Br. against Bleomycin induced chromosomal damage in cultured human lymphocytes, in vitro
المؤلفون:
Dhruti Mistry , Meonis Pithawala
المصدر:
Drug and chemical toxicology . 41(2)
سنة النشر:
2017
مصطلحات موضوعية:
0301 basic medicine , DNA Repair , Health, Toxicology and Mutagenesis , Lymphocyte , Pharmacology , Toxicology , law.invention , chemistry.chemical_compound , 0302 clinical medicine , law , Lymphocytes , Cells, Cultured , Antibiotics, Antineoplastic , biology , Plant Stems , General Medicine , G2 Phase Cell Cycle Checkpoints , medicine.anatomical_structure , 030220 oncology & carcinogenesis , visual_art , visual_art.visual_art_medium , Plant Bark , Bark , Alstonia scholaris , Bleomycin , complex mixtures , Risk Assessment , 03 medical and health sciences , Clastogen , medicine , Humans , Alstonia , Chromosome Aberrations , Chemical Health and Safety , Plants, Medicinal , Dose-Response Relationship, Drug , Plant Extracts , Methanol , Public Health, Environmental and Occupational Health , Water , biology.organism_classification , Plant Leaves , 030104 developmental biology , chemistry , Solvents , Phytotherapy
الوصف:
It is both interesting and necessary to identify and develop nontoxic radioprotective compounds. Bleomycin (BLM), a known radiomimetic drug was used as a clastogen in the present study. The possible protective effects against BLM (15 μg/ml) induced clastogenicity by aqueous and methanolic extracts from Alstonia scholaris bark, stem and leaves were compared. The treatment of bark extracts significantly (p
تدمد:
1525-6014
URL الوصول:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d12562020bdc68ec7da4e3f409ad61d https://pubmed.ncbi.nlm.nih.gov/28587522
رقم الأكسشن:
edsair.doi.dedup.....1d12562020bdc68ec7da4e3f409ad61d
قاعدة البيانات:
OpenAIRE