Protective effect of Alstonia scholaris Linn. R. Br. against Bleomycin induced chromosomal damage in cultured human lymphocytes, in vitro

التفاصيل البيبلوغرافية
العنوان: Protective effect of Alstonia scholaris Linn. R. Br. against Bleomycin induced chromosomal damage in cultured human lymphocytes, in vitro
المؤلفون: Dhruti Mistry, Meonis Pithawala
المصدر: Drug and chemical toxicology. 41(2)
سنة النشر: 2017
مصطلحات موضوعية: 0301 basic medicine, DNA Repair, Health, Toxicology and Mutagenesis, Lymphocyte, Pharmacology, Toxicology, law.invention, chemistry.chemical_compound, 0302 clinical medicine, law, Lymphocytes, Cells, Cultured, Antibiotics, Antineoplastic, biology, Plant Stems, General Medicine, G2 Phase Cell Cycle Checkpoints, medicine.anatomical_structure, 030220 oncology & carcinogenesis, visual_art, visual_art.visual_art_medium, Plant Bark, Bark, Alstonia scholaris, Bleomycin, complex mixtures, Risk Assessment, 03 medical and health sciences, Clastogen, medicine, Humans, Alstonia, Chromosome Aberrations, Chemical Health and Safety, Plants, Medicinal, Dose-Response Relationship, Drug, Plant Extracts, Methanol, Public Health, Environmental and Occupational Health, Water, biology.organism_classification, Plant Leaves, 030104 developmental biology, chemistry, Solvents, Phytotherapy
الوصف: It is both interesting and necessary to identify and develop nontoxic radioprotective compounds. Bleomycin (BLM), a known radiomimetic drug was used as a clastogen in the present study. The possible protective effects against BLM (15 μg/ml) induced clastogenicity by aqueous and methanolic extracts from Alstonia scholaris bark, stem and leaves were compared. The treatment of bark extracts significantly (p
تدمد: 1525-6014
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d12562020bdc68ec7da4e3f409ad61d
https://pubmed.ncbi.nlm.nih.gov/28587522
رقم الأكسشن: edsair.doi.dedup.....1d12562020bdc68ec7da4e3f409ad61d
قاعدة البيانات: OpenAIRE