Nonfat milk attenuates acute hyperglycemia in individuals with android obesity: A randomized control trial
| العنوان: | Nonfat milk attenuates acute hyperglycemia in individuals with android obesity: A randomized control trial |
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| المؤلفون: | Stephen J. Roy, Jisok Lim, Miriam P. Leary, Wonil Park, Jared Eaves, Hirofumi Tanaka, Rodrigo Ferrari, Daniel R. Machin |
| المصدر: | Food Science & Nutrition, Vol 6, Iss 8, Pp 2104-2112 (2018) Food Science & Nutrition, 6(8):2104-2112 Food Science & Nutrition |
| بيانات النشر: | Wiley, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | 0301 basic medicine, medicine.medical_specialty, medicine.medical_treatment, lcsh:TX341-641, flow‐mediated dilation, oral glucose tolerance test, Overweight, Placebo, abdominal obesity, law.invention, 03 medical and health sciences, Randomized controlled trial, law, Internal medicine, Medicine, Abdominal obesity, Original Research, 030109 nutrition & dietetics, business.industry, Insulin, dairy, flow-mediated dilation, Carbohydrate, Postprandial, Endocrinology, Android fat distribution, medicine.symptom, business, lcsh:Nutrition. Foods and food supply, Food Science |
| الوصف: | BACKGROUND Elevated android body fat increases the risk of developing cardiometabolic diseases. Postprandial hyperglycemia contributes to the proatherogenic metabolic state evident in android adiposity. Due to the insulinotropic effect of milk‐derived proteins, postprandial hyperglycemia has been shown to be reduced with the addition of dairy products. The purpose of this study was to determine whether one serving of nonfat milk added to an oral glucose tolerance test (OGTT ) could attenuate postprandial hyperglycemia in individuals with elevated android adiposity and whether these improvements would be associated with metabolic and/or peripheral hemodynamic effects. METHODS In this placebo‐controlled, randomized, crossover experimental study, 29 overweight/obese adults (26 ± 1 year) consumed an OGTT beverage (75 g glucose) combined with either nonfat milk (227 g) or a placebo control (12 g lactose + 8 g protein + 207 g water) that was matched for both carbohydrate and protein quantities. RESULTS In the whole sample, blood glucose and insulin concentrations increased over time in both trials with no significant differences between trials. Relative increases in peak blood glucose response were significantly related to android body fat (p < 0.05). The subjects in the highest tertiles of android body fat displayed attenuated hyperglycemic responses as well as improvements in flow‐mediated dilation (FMD) after milk intake. CONCLUSIONS A single serving of nonfat milk may attenuate acute hyperglycemia in individuals with elevated android body fat offering a simple and convenient option for managing elevations in blood glucose. |
| تدمد: | 2048-7177 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e884281bd833860893dbe06da4e8316 https://doi.org/10.1002/fsn3.767 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....1e884281bd833860893dbe06da4e8316 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20487177 |
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