Incidence, Risk Factors and Outcome of Suspected Central Venous Catheter-related Infections in Critically Ill COVID-19 Patients
| العنوان: | Incidence, Risk Factors and Outcome of Suspected Central Venous Catheter-related Infections in Critically Ill COVID-19 Patients |
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| المؤلفون: | Smit, Jasper M., Exterkate, Lotte, Van Tienhoven, Arne J., Haaksma, Mark E., Heldeweg, Micah L.A., Fleuren, Lucas, Thoral, Patrick, Dam, Tariq A., Heunks, Leo M.A., Gommers, Diederik, Cremer, Olaf L., Bosman, Rob J., Rigter, Sander, Wils, Evert Jan, Frenzel, Tim, Vlaar, Alexander P., Dongelmans, Dave A., De Jong, Remko, Peters, Marco, Kamps, Marlijn J.A., Ramnarain, Dharmanand, Nowitzky, Ralph, Nooteboom, Fleur G.C.A., De Ruijter, Wouter, Urlings-Strop, Louise C., Smit, Ellen G.M., Mehagnoul-Schipper, D. Jannet, Dormans, Tom, De Jager, Cornelis P.C., Hendriks, Stefaan H.A., Achterberg, Sefanja, Oostdijk, Evelien, Reidinga, Auke C., Festen-Spanjer, Barbara, Brunnekreef, Gert B., Cornet, Alexander D., Van Den Tempel, Walter, Boelens, Age D., Koetsier, Peter, Lens, Judith, Faber, Harald J., Karakus, A., Entjes, Robert, De Jong, Paul, Rettig, Thijs C.D., Arbous, Sesmu, Vonk, Bas, Machado, Tomas, Girbes, Armand R.J., Sieswerda, Elske, Elbers, Paul W.G., Tuinman, Pieter R. |
| المساهمون: | Intensive care medicine, Radiology and nuclear medicine, Anesthesiology, Internal medicine, ACS - Diabetes & metabolism, ACS - Microcirculation, Amsterdam Cardiovascular Sciences, Cardio-thoracic surgery, General practice, AII - Infectious diseases, Medical Microbiology and Infection Prevention, ACS - Pulmonary hypertension & thrombosis, Intensive Care Medicine, APH - Quality of Care, Graduate School, AII - Cancer immunology, CCA - Cancer biology and immunology, Intensive Care |
| المصدر: | Shock, 58, 5, pp. 358-365 Shock, 58, 358-365 Shock, 58(5), 358-365. Lippincott Williams and Wilkins Shock: Injury, Inflammation and Sepsis, 58(5), 358-365. LIPPINCOTT WILLIAMS & WILKINS Shock (Augusta, Ga.), 58(5), 358-365. Lippincott Williams and Wilkins Smit, J M, Exterkate, L, van Tienhoven, A J, Haaksma, M E, Heldeweg, M L A, Fleuren, L, Thoral, P, Dam, T A, Heunks, L M A, Gommers, D, Cremer, O L, Bosman, R J, Rigter, S, Wils, E-J, Frenzel, T, Vlaar, A P, Dongelmans, D A, de Jong, R, Peters, M, Kamps, M J A, Ramnarain, D, Nowitzky, R, Nooteboom, F G C A, de Ruijter, W, Urlings-Strop, L C, Smit, E G M, Mehagnoul-Schipper, D J, Dormans, T, de Jager, C P C, Hendriks, S H A, Achterberg, S, Oostdijk, E, Reidinga, A C, Festen-Spanjer, B, Brunnekreef, G B, Cornet, A D, van den Tempel, W, Boelens, A D, Koetsier, P, Lens, J, Faber, H J, Karakus, A, Entjes, R, de Jong, P, Rettig, T C D, Arbous, S, Vonk, B, Machado, T, Girbes, A R J, Sieswerda, E, Elbers, P W G & Tuinman, P R 2022, ' Incidence, Risk Factors and Outcome of Suspected Central Venous Catheter-related Infections in Critically Ill COVID-19 Patients : A Multicenter Retrospective Cohort Study ', Shock, vol. 58, no. 5, pp. 358-365 . https://doi.org/10.1097/SHK.0000000000001994 Shock, 58(5), 358-365. Lippincott Williams & Wilkins |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | catheter-related infections, Catheterization, Central Venous, Critical Illness, Incidence, Other Research Radboud Institute for Health Sciences [Radboudumc 0], COVID-19, Critical Care and Intensive Care Medicine, Central venous catheters, All institutes and research themes of the Radboud University Medical Center, Risk Factors, Emergency Medicine, Humans, Retrospective Studies, intensive care |
| الوصف: | Background: Aims of this study were to investigate the prevalence and incidence of catheter-related infection, identify risk factors, and determine the relation of catheter-related infection with mortality in critically ill COVID-19 patients. Methods: This was a retrospective cohort study of central venous catheters (CVCs) in critically ill COVID-19 patients. Eligible CVC insertions required an indwelling time of at least 48 hours and were identified using a full-admission electronic health record database. Risk factors were identified using logistic regression. Differences in survival rates at day 28 of follow-up were assessed using a log-rank test and proportional hazard model. Results: In 538 patients, a total of 914 CVCs were included. Prevalence and incidence of suspected catheter-related infection were 7.9% and 9.4 infections per 1,000 catheter indwelling days, respectively. Prone ventilation for more than 5 days was associated with increased risk of suspected catheter-related infection; odds ratio, 5.05 (95% confidence interval 2.12-11.0). Risk of death was significantly higher in patients with suspected catheter-related infection (hazard ratio, 1.78; 95% confidence interval, 1.25-2.53). Conclusions: This study shows that in critically ill patients with COVID-19, prevalence and incidence of suspected catheter-related infection are high, prone ventilation is a risk factor, and mortality is higher in case of catheter-related infection. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1073-2322 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e9e46df27ec6c67d70e3919bf8cbda9 https://doi.org/10.1097/shk.0000000000001994 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....1e9e46df27ec6c67d70e3919bf8cbda9 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10732322 |
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