High throughput screening of photocatalytic conversion of pharmaceutical contaminants in water
| العنوان: | High throughput screening of photocatalytic conversion of pharmaceutical contaminants in water |
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| المؤلفون: | Nelson Ribeiro, David Barata, Joana Romão, Guido Mul, Hugo Fernandes, Pamela Habibovic |
| المساهمون: | Photocatalytic Synthesis, RS: MERLN - Instructive Biomaterials Engineering (IBE), Division Instructive Biomaterials Eng |
| المصدر: | Environmental Pollution, 220(Part B), 1199-1207. Elsevier Environmental Pollution, 220, 1199-1207. ELSEVIER SCI LTD |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Health, Toxicology and Mutagenesis, High-throughput screening, 02 engineering and technology, 010501 environmental sciences, Conjugated system, Toxicology, 01 natural sciences, Catalysis, chemistry.chemical_compound, Reactant selectivity, WASTE-WATER, High throughput screening, Organic chemistry, Molecule, Water treatment, Photocatalysis, 0105 earth and related environmental sciences, Titanium, PURIFICATION, Photolysis, Chemistry, Water, General Medicine, Environmental Exposure, DEGRADATION, Hydrogen-Ion Concentration, 021001 nanoscience & nanotechnology, Pollution, Pharmaceutical compounds, High-Throughput Screening Assays, Pharmaceutical Preparations, Titanium dioxide, 2023 OA procedure, Degradation (geology), TIO2, 0210 nano-technology, Oxidation-Reduction, Water Pollutants, Chemical, Environmental Monitoring |
| الوصف: | The susceptibility for photon-induced degradation of over 800 pharmaceutical compounds present in the LOPAC(1280) library, was analyzed by UV/Vis spectroscopy in the absence or presence of TiO2 P25 in water. In general, few compounds were effectively degraded in the absence of the TiO2 photocatalyst (3% of all compounds tested), while in the presence of TiO2, the majority of compounds was converted, often to a large degree. Differences in degree of degradation are evaluated on the basis of molecular weight, as well as the chemical nature of the drug compounds (functional groups and pharmacological classes). In general, if the molecular weight increases, the degradation efficacy decreases. Relatively high degrees of conversion can be achieved for (relatively small) molecules with functional groups such as aldehydes, alcohols, ketones and nitriles. A low degree of conversion was observed for compounds composed of conjugated aromatic systems. Trends in degradation efficacy on the basis of pharmacological class, e.g. comparing hormones and opioids, are not obvious. (C) 2016 Elsevier Ltd. All rights reserved. |
| وصف الملف: | application/pdf |
| تدمد: | 1873-6424 0269-7491 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f1c4575cffa71acb64a9ba70fd81275 https://pubmed.ncbi.nlm.nih.gov/27839992 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....1f1c4575cffa71acb64a9ba70fd81275 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 18736424 02697491 |
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