Novel approaches for the treatment of infections due to multidrug-resistant bacterial pathogens
| العنوان: | Novel approaches for the treatment of infections due to multidrug-resistant bacterial pathogens |
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| المؤلفون: | Mohmmad Imran, Mohammad Naiyaz Ahmad, Arunava Dasgupta, Preeti Rana, Nanduri Srinivas, Sidharth Chopra |
| المصدر: | Future Medicinal Chemistry. 14:1133-1148 |
| بيانات النشر: | Future Science Ltd, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Pharmacology, Anti-Infective Agents, Drug Resistance, Multiple, Bacterial, Drug Discovery, Humans, Molecular Medicine, Bacterial Infections, Anti-Bacterial Agents |
| الوصف: | Antimicrobial resistance (AMR), which is a major challenge for global healthcare, emerging because of several reasons including overpopulation, increased global migration and selection pressure due to enhanced use of antibiotics. Antibiotics are the widely used therapeutic options to combat infectious diseases; however, unfortunately, inadequate and irregular antibiotic courses are also major contributing factors in the emergence of AMR. Additionally, persistent failure to develop and commercialize new antibiotics has created the scarcity of effective anti-infective drugs. Thus, there is an urgent need for a new class of antimicrobials and other novel approaches to curb the menace of AMR. Besides the conventional approaches, some novel approaches such as the use of antimicrobial peptides, bacteriophages, immunomodulation, host-directed therapy and antibodies have shown really promising potentials. |
| تدمد: | 1756-8927 1756-8919 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::201df6946534dfbeafacea95cb7227ac https://doi.org/10.4155/fmc-2022-0029 |
| رقم الأكسشن: | edsair.doi.dedup.....201df6946534dfbeafacea95cb7227ac |
| قاعدة البيانات: | OpenAIRE |
PDF full text from Publisher | تدمد: | 17568927 17568919 |
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