Outcomes of esophagectomy for patients with esophageal squamous cell carcinoma accompanied by recurrent laryngeal nerve palsy at diagnosis
| العنوان: | Outcomes of esophagectomy for patients with esophageal squamous cell carcinoma accompanied by recurrent laryngeal nerve palsy at diagnosis |
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| المؤلفون: | Takashi Hashimoto, Daisuke Fujiwara, Asako Ozaki, Yoshiaki Kajiyama, Shinji Mine, Tadasuke Hashiguchi, Masahiko Tsurumaru, Atsushi Arakawa, Motomi Nasu, Kouhei Yoshino |
| المصدر: | Esophagus. 19:233-239 |
| بيانات النشر: | Springer Science and Business Media LLC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, Esophageal Neoplasms, Recurrent laryngeal nerve palsy, business.industry, medicine.medical_treatment, Gastroenterology, Esophageal cancer, medicine.disease, Esophageal squamous cell carcinoma, Surgery, Esophagectomy, Surgical oncology, Cardiothoracic surgery, medicine, Paralysis, Recurrent laryngeal nerve, Humans, Lymph Node Excision, Esophageal Squamous Cell Carcinoma, medicine.symptom, business, Vocal Cord Paralysis, Aged |
| الوصف: | Background Hoarseness is one of the classical symptoms in patients with locally advanced thoracic esophageal squamous cell carcinoma (ESCC), and it results from recurrent laryngeal nerve palsy, which is caused by nodal metastasis along the recurrent laryngeal nerve or by main tumors. We reviewed the short-term and long-term results of esophagectomy for patients with locally advanced ESCC and hoarseness at diagnosis. Patients Patients who initially presented with hoarseness from recurrent laryngeal nerve palsy between 2009 and 2018 and underwent esophagectomy for thoracic ESCC were eligible for this study. Pharyngolaryngectomy or cervical ESCC were exclusionary. Results A total of 15 patients were eligible, and 14 underwent resection of the recurrent laryngeal nerves. The remaining patient had nerve-sparing surgery. Nine patients (60%) had post-operative complications ≥ Clavien–Dindo class II and, pulmonary complications were most common. Two patients (13%) died in the hospital. The 5-year overall survival rate for all patients was 16%. Age (≤ 65 years), cT1/T2 tumor, and remarkably good response to neoadjuvant treatment were likely related to longer survival; however, these relationships were not statistically significant. Conclusions Esophagectomy for ESCC patients who are diagnosed with recurrent laryngeal nerve paralysis at initial presentation could be a treatment option if the patient is relatively young, has a cT1/T2 tumor, or shows a remarkably good response to neoadjuvant treatment. However, clinicians should be aware of the possibility of postoperative pulmonary complications, which were frequently observed with the procedure. |
| تدمد: | 1612-9067 1612-9059 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20357f93a33f08d1a291e7c267067ad3 https://doi.org/10.1007/s10388-021-00890-6 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....20357f93a33f08d1a291e7c267067ad3 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 16129067 16129059 |
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