أعرض في EDS

Cytochrome P450 2D6 Polymorphism Is a Molecular Genetic Marker of Liver Cirrhosis Progression

التفاصيل البيبلوغرافية
العنوان: Cytochrome P450 2D6 Polymorphism Is a Molecular Genetic Marker of Liver Cirrhosis Progression
المؤلفون: E. V. Vinogradova, Svetlana V. Aidagulova, O. A. Postnikova, E. G. Shchepotina, D. L. Nepomnyashchikh, S. I. Makarova, Yu. Yu. Karavaeva, V. V. Lyakhovich, V. A. Vavilin, Zh. V. Nokhrina
المصدر: Bulletin of Experimental Biology and Medicine. 152:633-636
بيانات النشر: Springer Science and Business Media LLC, 2012.
سنة النشر: 2012
مصطلحات موضوعية: Adult, Genetic Markers, Liver Cirrhosis, Male, Hepatitis B virus, Heterozygote, medicine.medical_specialty, CYP2D6, Cirrhosis, Liver fibrosis, Hepacivirus, Biology, Polymorphism, Single Nucleotide, Gastroenterology, White People, General Biochemistry, Genetics and Molecular Biology, chemistry.chemical_compound, Internal medicine, Genotype, medicine, Humans, Genetic Predisposition to Disease, Aged, Toxic cirrhosis, Hepatitis, Alcoholic, Homozygote, General Medicine, Middle Aged, Hepatitis B, medicine.disease, Hepatitis C, Siberia, Cytochrome P-450 CYP2D6, Liver, chemistry, Genetic marker, Immunology, Disease Progression, Female, Xenobiotic
الوصف: Patients with infectious viral or toxic cirrhosis of the liver participated in complex clinical pathomorphological and molecular-genetic study aimed at the search for markers of predisposition to accelerated liver fibrosis, in which the xenobiotic biotransformation system is involved. The results demonstrate association between CYP2D6 (1846 G/A) genotype and rapid cirrhosis development and indicate the necessity of studying the mechanisms underlying this association.
تدمد: 1573-8221
0007-4888
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21102b7506b793c285219c502416f60f
https://doi.org/10.1007/s10517-012-1595-x
حقوق: CLOSED
رقم الأكسشن: edsair.doi.dedup.....21102b7506b793c285219c502416f60f
قاعدة البيانات: OpenAIRE
الوصف
تدمد:15738221
00074888