Genetic control of root growth: from genes to networks
| العنوان: | Genetic control of root growth: from genes to networks |
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| المؤلفون: | Takehiko Ogura, Santosh B. Satbhai, Wolfgang Busch, Daniela Ristova, Radka Slovak |
| المصدر: | Annals of Botany. 117:9-24 |
| بيانات النشر: | Oxford University Press (OUP), 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | 0301 basic medicine, Genetics, Root (linguistics), Invited Review, biology, Systems Biology, Systems biology, fungi, Gene regulatory network, food and beverages, Genomics, Plant Science, Computational biology, Plants, Genes, Plant, biology.organism_classification, Models, Biological, Plant Roots, 03 medical and health sciences, 030104 developmental biology, Phenomics, Arabidopsis thaliana, Gene Regulatory Networks, Gene, Lateral root formation |
| الوصف: | Background Roots are essential organs for higher plants. They provide the plant with nutrients and water, anchor the plant in the soil, and can serve as energy storage organs. One remarkable feature of roots is that they are able to adjust their growth to changing environments. This adjustment is possible through mechanisms that modulate a diverse set of root traits such as growth rate, diameter, growth direction and lateral root formation. The basis of these traits and their modulation are at the cellular level, where a multitude of genes and gene networks precisely regulate development in time and space and tune it to environmental conditions. Scope This review first describes the root system and then presents fundamental work that has shed light on the basic regulatory principles of root growth and development. It then considers emerging complexities and how they have been addressed using systems-biology approaches, and then describes and argues for a systems-genetics approach. For reasons of simplicity and conciseness, this review is mostly limited to work from the model plant Arabidopsis thaliana, in which much of the research in root growth regulation at the molecular level has been conducted. Conclusions While forward genetic approaches have identified key regulators and genetic pathways, systemsbiology approaches have been successful in shedding light on complex biological processes, for instance molecular mechanisms involving the quantitative interaction of several molecular components, or the interaction of large numbers of genes. However, there are significant limitations in many of these methods for capturing dynamic processes, as well as relating these processes to genotypic and phenotypic variation. The emerging field of systems genetics promises to overcome some of these limitations by linking genotypes to complex phenotypic and molecular data using approaches from different fields, such as genetics, genomics, systems biology and phenomics. |
| تدمد: | 1095-8290 0305-7364 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2133cbed7655e06692d3b22fa646c6ca https://doi.org/10.1093/aob/mcv160 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....2133cbed7655e06692d3b22fa646c6ca |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10958290 03057364 |
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