Bifunctional Silica-Coated Superparamagnetic FePt Nanoparticles for Fluorescence/MR Dual Imaging
| العنوان: | Bifunctional Silica-Coated Superparamagnetic FePt Nanoparticles for Fluorescence/MR Dual Imaging |
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| المؤلفون: | Chia-Yen Hsu, Syu-Ming Lai, Ping-Shan Lai, Tsiao-Yu Tsai, Jai-Lin Tsai, Ming-Yuan Liao |
| المصدر: | Journal of Nanomaterials, Vol 2012 (2012) |
| بيانات النشر: | Hindawi Limited, 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Materials science, Article Subject, medicine.diagnostic_test, Nanoparticle, Nanotechnology, Magnetic resonance imaging, Fluorescence, Dual imaging, chemistry.chemical_compound, Nuclear magnetic resonance, chemistry, Nanotoxicology, lcsh:Technology (General), medicine, lcsh:T1-995, General Materials Science, Fluorescein, Bifunctional, Superparamagnetism |
| الوصف: | Recently, superparamagnetic chemically disordered face-centered cubic (fcc) FePt nanoparticles have been demonstrated as superior negative contrast agents for magnetic resonance imaging (MRI). However, their low intracellular labeling efficiency has limited the potential usage and the nanotoxicity of the particles requires attention. We have developed fluorescein isothiocyanate-incorporated silica-coated FePt (FePt@SiO2-FITC) nanoparticles that exhibited not only a significantT1andT2MR contrast abilities but also a fluorescent property without significant cytotoxicities. These results suggest that silica-coated superparamagnetic FePt nanoparticles are potential nanodevices for the combination of fluorescence and MRI contrast used for cancer diagnosis. |
| وصف الملف: | text/xhtml |
| تدمد: | 1687-4129 1687-4110 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21c15170b9c3ddfd55499ea80d8022e4 https://doi.org/10.1155/2012/631584 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....21c15170b9c3ddfd55499ea80d8022e4 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16874129 16874110 |
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