Immediate and late outcomes of stenting for severe extracranial internal carotid artery stenosis in octogenarian patients

التفاصيل البيبلوغرافية
العنوان: Immediate and late outcomes of stenting for severe extracranial internal carotid artery stenosis in octogenarian patients
المؤلفون: Hao Xiao, Xiong Zhang, Jiayi Zhong, Chengbo Dai, Jian-Wei Mo, Shu-Wen Xu, Shuyuan Wang, Zhanyi Lin, Faxin Ma, Jin-Hai Duan
المصدر: Brain and Behavior
بيانات النشر: John Wiley and Sons Inc., 2017.
سنة النشر: 2017
مصطلحات موضوعية: Male, medicine.medical_specialty, China, survival duration RRID: SCR_002865, medicine.medical_treatment, Population, stenting, Long Term Adverse Effects, 030204 cardiovascular system & hematology, Revascularization, Asymptomatic, 03 medical and health sciences, Behavioral Neuroscience, Blood Vessel Prosthesis Implantation, 0302 clinical medicine, Life Expectancy, Postoperative Complications, medicine.artery, medicine, Humans, Minimally Invasive Surgical Procedures, Carotid Stenosis, Myocardial infarction, education, Stroke, Original Research, Retrospective Studies, Aged, 80 and over, education.field_of_study, business.industry, Patient Selection, stenosis, extracranial internal carotid artery, Retrospective cohort study, medicine.disease, stroke, Survival Analysis, Surgery, Stenosis, Female, Stents, Internal carotid artery, medicine.symptom, business, 030217 neurology & neurosurgery, Carotid Artery, Internal
الوصف: Background Multiple studies suggest that internal carotid artery stenting can be performed safely in octogenarians with low periprocedural complication rates. However, great concern still exists as to whether these patients will gain long‐term benefits from this procedure given their advanced age and uncertain life expectancy. We decided to conduct a retrospective study to determine short‐and long‐term clinical outcomes and to analyze survival duration in this population. Methods and Results Sixty‐nine consecutive elderly patients with either symptomatic or asymptomatic stenosis ≥70% underwent 86 procedures. Immediate and late outcomes, as well as survival data, were analyzed retrospectively. Mean age was 83.1 ± 2.7 years. Mean survival was 49.3 ± 10.1 months. A complete neurological assessment was obtained at 1 and 2 years in 100% of patients, at 3 years in 90.7% of patients and at 5 years in 84.8% of patients. Two major and one minor ischemic strokes occurred during the periprocedural period. No death, myocardial infarction or intracranial hemorrhage was recorded. The mean follow‐up period was 55.4 ± 24.6 months. Four patients experienced a minimum of 1 year of follow‐up, and the longest is 8 years. Among the patients with the longest follow‐up time, 6 had ischemic strokes, of which 2 were fatal. In total, 17 deaths occurred. Four patients experienced dementia without stroke. Survival at 3 and 5 years was estimated to be 90% and 73%, respectively. Conclusion This study demonstrated that stenting in octogenarians was safe and effective during the periprocedural period. Long‐term follow‐up showed a low rate of fatal and nonfatal stroke, and patients survived long enough to benefit from the procedure. However, it was associated with a relatively high rate of long‐term event. Though carotid artery stenting is a minimally invasive procedure, it should still be performed with great caution and only in carefully selected patients. The present study suggested that in this age population, carotid artery stenting might be considered as a revascularization option.
اللغة: English
تدمد: 2162-3279
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22a95832f9072435fd648300852b1695
http://europepmc.org/articles/PMC5853617
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....22a95832f9072435fd648300852b1695
قاعدة البيانات: OpenAIRE