DistributedFBA. jl: high-level, high-performance flux balance analysis in Julia
| العنوان: | DistributedFBA. jl: high-level, high-performance flux balance analysis in Julia |
|---|---|
| المؤلفون: | Ines Thiele, Laurent Heirendt, Ronan M. T. Fleming |
| المساهمون: | National Centre of Excellence in Research (NCER) on Parkinson’s disease [sponsor], Luxembourg National Research Fund (FNR) ATTRACT program grant (FNR/A12/01) [sponsor], U.S. Department of Energy, Offices of Advanced Scientific Computing Research and the Biological and Environmental Research as part of the Scientific Discovery Through Advanced Computing program, grant no. DE-SC0010429 [sponsor], Luxembourg Centre for Systems Biomedicine (LCSB): Systems Biochemistry (Fleming Group) [research center], Luxembourg Centre for Systems Biomedicine (LCSB): Molecular Systems Physiology (Thiele Group) [research center] |
| المصدر: | Bioinformatics, 33(9), 1421-1423. Oxford University Press Bioinformatics Bioinformatics. Oxford University Press (2017). |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Parallel computing, 0301 basic medicine, Statistics and Probability, Computer science, Distributed computing, 0206 medical engineering, Metabolic networks, 02 engineering and technology, Biochemistry, biophysics & molecular biology [F05] [Life sciences], Quantitative Biology - Quantitative Methods, Biochemistry, Models, Biological, Computational science, Multidisciplinaire, généralités & autres [C99] [Ingénierie, informatique & technologie], 03 medical and health sciences, Flux variability analysis, Code (cryptography), Biochimie, biophysique & biologie moléculaire [F05] [Sciences du vivant], Molecular Biology, Quantitative Methods (q-bio.QM), Systems Biology, Multidisciplinary, general & others [C99] [Engineering, computing & technology], Computational Biology, Computational modeling, Applications Notes, Computer Science Applications, Flux balance analysis, Computational Mathematics, 030104 developmental biology, Computational Theory and Mathematics, FOS: Biological sciences, Flux (metabolism), 020602 bioinformatics, Metabolic Networks and Pathways, Software |
| الوصف: | Motivation: Flux balance analysis, and its variants, are widely used methods for predicting steady-state reaction rates in biochemical reaction networks. The exploration of high dimensional networks with such methods is currently hampered by software performance limitations. Results: DistributedFBA.jl is a high-level, high-performance, open-source implementation of flux balance analysis in Julia. It is tailored to solve multiple flux balance analyses on a subset or all the reactions of large and huge-scale networks, on any number of threads or nodes. Availability: The code and benchmark data are freely available on http://github.com/opencobra/COBRA.jl. The documentation can be found at http://opencobra.github.io/COBRA.jl Comment: 2 pages, 1 figure. Supplementary Material: 1 page |
| وصف الملف: | application/pdf |
| اللغة: | English |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::233eccb6c93c0a341f4f21a29ef5f5fb http://hdl.handle.net/1887/71470 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....233eccb6c93c0a341f4f21a29ef5f5fb |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |