Lurasidone in the Treatment of Bipolar Depression: Systematic Review of Systematic Reviews
| العنوان: | Lurasidone in the Treatment of Bipolar Depression: Systematic Review of Systematic Reviews |
|---|---|
| المؤلفون: | Michele Fornaro, Domenico De Berardis, André F. Carvalho, Giampaolo Perna, Cristiano A. Köhler, Felice Iasevoli, Marco Solmi, Laura Orsolini, Nicola Veronese, Andrea de Bartolomeis, Elisabetta F. Buonaguro |
| المساهمون: | Fornaro, Michele, De Berardis, Domenico, Perna, Giampaolo, Solmi, Marco, Veronese, Nicola, Orsolini, Laura, Buonaguro, ELISABETTA FILOMENA, Iasevoli, Felice, Köhler, Cristiano André, Carvalho, André Ferrer, DE BARTOLOMEIS, Andrea, Fornaro, M., De Berardis, D., Perna, G., Solmi, M., Veronese, N., Orsolini, L., Buonaguro, E.F., Iasevoli, F., Köhler, C.A., Carvalho, A.F., De Bartolomeis, A. |
| المصدر: | BioMed Research International, Vol 2017 (2017) Repositório Institucional da Universidade Federal do Ceará (UFC) Universidade Federal do Ceará (UFC) instacron:UFC BioMed Research International |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Genetics and Molecular Biology (all), Transtorno Bipolar, medicine.medical_specialty, Bipolar Disorder, Immunology and Microbiology (all), Concordance, Drug profile, Alternative medicine, MEDLINE, lcsh:Medicine, Review Article, Biochemistry, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Lurasidone Hydrochloride, 0302 clinical medicine, Biochemistry, Genetics and Molecular Biology (all), medicine, Bipolar Depression, Humans, Psychiatry, Drug Approval, Depression (differential diagnoses), Lurasidone, General Immunology and Microbiology, business.industry, lcsh:R, General Medicine, 030227 psychiatry, Systematic review, Tolerability, Depressão, business, 030217 neurology & neurosurgery, medicine.drug |
| الوصف: | Introduction. A burgeoning number of systematic reviews considering lurasidone in the treatment of bipolar depression have occurred since its Food and Drug Administration extended approval in 2013. While a paucity of available quantitative evidence still precludes preliminary meta-analysis on the matter, the present quality assessment of systematic review of systematic reviews, nonetheless, aims at highlighting current essential information on the topic. Methods. Both published and unpublished systematic reviews about lurasidone mono- or adjunctive therapy in the treatment of bipolar depression were searched by two independent authors inquiring PubMed/Cochrane/Embase/Scopus from inception until October 2016. Results. Twelve included systematic reviews were of moderate-to-high quality and consistent in covering the handful of RCTs available to date, suggesting the promising efficacy, safety, and tolerability profile of lurasidone. Concordance on the drug profile seems to be corroborated by a steadily increasing number of convergent qualitative reports on the matter. Limitations. Publication, sponsorship, language, citation, and measurement biases. Conclusions. Despite being preliminary in nature, this overview stipulates the effectiveness of lurasidone in the acute treatment of Type I bipolar depression overall. As outlined by most of the reviewed evidence, recommendations for future research should include further controlled trials of extended duration. |
| اللغة: | English |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::249dade0354d2fe4840f6f877e584a83 http://hdl.handle.net/11588/679375 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....249dade0354d2fe4840f6f877e584a83 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |