Cognitive–behavioural therapy for patients with schizophrenia: a multicentre randomized controlled trial in Beijing, China
| العنوان: | Cognitive–behavioural therapy for patients with schizophrenia: a multicentre randomized controlled trial in Beijing, China |
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| المؤلفون: | Zi-Yan Xu, Xiangqun Wang, Zhanjiang Li, Douglas Turkington, Li-Qiong Yan, Roger M. K. Ng, Zhi-Hua Guo, David Kingdon, Na Wang, Jing Sun, Ying Qu |
| المصدر: | Psychological Medicine. 45:1893-1905 |
| بيانات النشر: | Cambridge University Press (CUP), 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Adult, Male, behavioral disciplines and activities, law.invention, Young Adult, Randomized controlled trial, law, mental disorders, medicine, Humans, Single-Blind Method, Applied Psychology, Social functioning, Cognitive Behavioral Therapy, Positive and Negative Syndrome Scale, Cognition, medicine.disease, Combined Modality Therapy, Psychiatry and Mental health, Treatment Outcome, Schizophrenia, Supportive psychotherapy, Beijing, Female, Psychology, Social Adjustment, Antipsychotic Agents, Psychopathology, Clinical psychology |
| الوصف: | BackgroundMeta-analyses support the efficacy of cognitive–behavioural therapy (CBT) for schizophrenia in western cultures. This study aimed to compare the efficacy of CBT and supportive therapy (ST) for patients with schizophrenia in China.MethodA multicentre randomized controlled, single-blinded, parallel-group trial enrolled a sample of 192 patients with schizophrenia. All patients were offered 15 sessions of either CBT or ST over 24 weeks and followed up for an additional 60 weeks. All measures used were standardized instruments with good reliability and validity. The Positive and Negative Syndrome Scale (PANSS) was used to assess symptoms of schizophrenia. The Schedule for Assessing Insight (SAI) was used to assess patients’ insight and the Personal and Social Performance Scale (PSP) was used to assess their social functioning.ResultsEffect-size analysis showed that patients made rapid improvements in all symptoms, insight and social functioning as measured by the PANSS, SAI and PSP at 12 and 24 weeks and maintained these improvements over the course of the study to 84 weeks. Patients in the CBT group showed significantly greater and more durable improvement in PANSS total score (p = 0.045, between-groupd = 0.48), positive symptoms (p = 0.018, between-groupd = 0.42) and social functioning (p = 0.037, between-groupd = 0.64), with significant differences emerging after completion of therapy.ConclusionsBoth CBT and ST combined with medication had benefits on psychopathology, insight and social functioning of patients with schizophrenia. CBT was significantly more effective than ST on overall, positive symptoms and social functioning of patients with schizophrenia in the long term. |
| وصف الملف: | text |
| تدمد: | 1469-8978 0033-2917 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24b15872223ba901284f73f48c3cee4f https://doi.org/10.1017/s0033291714002992 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....24b15872223ba901284f73f48c3cee4f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14698978 00332917 |
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