Impact of Subjective and Objective Sleep Quality on Peptic Ulcer Rebleeding in Older Adults
| العنوان: | Impact of Subjective and Objective Sleep Quality on Peptic Ulcer Rebleeding in Older Adults |
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| المؤلفون: | Danyu Li, Ruirui Xu, Jian Hu, Gengzhen Chen, Boye Fang, Shuyan Yang, Huiying Liu |
| المصدر: | Psychosomatic Medicine. 83:995-1003 |
| بيانات النشر: | Ovid Technologies (Wolters Kluwer Health), 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Peptic Ulcer, medicine.medical_specialty, Multivariate analysis, medicine.diagnostic_test, business.industry, Esophagogastroduodenoscopy, Hazard ratio, Disease, Sleep in non-human animals, Pittsburgh Sleep Quality Index, Psychiatry and Mental health, Peptic Ulcer Hemorrhage, Sleep Quality, Recurrence, Risk Factors, Internal medicine, Etiology, Humans, Medicine, Sleep onset latency, business, Applied Psychology, Aged |
| الوصف: | OBJECTIVE This study aimed to examine the association of subjective and objective sleep quality with subsequent peptic ulcer rebleeding among older patients. METHODS Of 1196 older patients with peptic ulcer bleeding (PUB) recruited from 12 grade A hospitals in the People's Republic of China, 1106 achieved full recovery from PUB, and they were followed up for up to 30 days. Using multiple measures at 1-week intervals, patients who presented PUB symptoms were invited to have an esophagogastroduodenoscopy examination. Subjective sleep quality was measured using the Pittsburgh Sleep Quality Index. Objective sleep quality domains were measured using an accelerometer, including sleep onset latency, sleep efficiency, total sleep time, and the number of awakenings. RESULTS This study documented a 30-day cumulative ulcer rebleeding rate of 15.3%. Multivariate analyses showed that longer sleep onset latency (hazard ratio [HR] = 2.136 [1.336-2.558]) and more nighttime awakenings (HR = 1.698 [1.169-2.666]) increased the risk of ulcer rebleeding. However, a longer total sleep time (HR = 0.768 [0.698-0.887]) and better sleep efficiency (HR = 0.795 [0.682-0.975]) protected against ulcer rebleeding. Older patients who perceived poorer sleep quality were also more likely to experience ulcer rebleeding (HR = 2.295 [1.352-3.925]). CONCLUSIONS The present results highlight the importance of proper treatment and prevention of sleep problems in older adults after successful PUB treatment. Our results, if replicable in future studies with more rigorous design and representative samples, might shed light on the etiology of ulcer rebleeding and suggest new pathways for preventing this disease. |
| تدمد: | 1534-7796 0033-3174 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::272f07569df5c50a953ba037e406ead9 https://doi.org/10.1097/psy.0000000000001001 |
| رقم الأكسشن: | edsair.doi.dedup.....272f07569df5c50a953ba037e406ead9 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15347796 00333174 |
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