Respiratory mechanics in ventilated COPD patients: forced oscillation versus occlusion techniques
| العنوان: | Respiratory mechanics in ventilated COPD patients: forced oscillation versus occlusion techniques |
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| المؤلفون: | M. Rotger, Miquel Ferrer, Daniel Navajas, Ramon Farré, A. Torres |
| المصدر: | European Respiratory Journal. 12:170-176 |
| بيانات النشر: | European Respiratory Society (ERS), 1998. |
| سنة النشر: | 1998 |
| مصطلحات موضوعية: | Pulmonary and Respiratory Medicine, Artificial ventilation, medicine.medical_specialty, Pathology, medicine.medical_treatment, Respiratory physiology, Internal medicine, medicine, Humans, Lung Diseases, Obstructive, Respiratory system, Monitoring, Physiologic, Mechanical ventilation, COPD, business.industry, Airway Resistance, Respiratory disease, Muscle, Smooth, Equipment Design, medicine.disease, Respiration, Artificial, Intensive Care Units, Treatment Outcome, medicine.anatomical_structure, Respiratory failure, Respiratory Mechanics, Cardiology, business, Respiratory tract |
| الوصف: | The respiratory mechanics of artificially ventilated chronic obstructive pulmonary disease (COPD) patients were investigated by means of the forced oscillation (FOT) and the end-inspiratory airway occlusion (AOT) techniques. FOT was applied to measure respiratory resistance (Rrs) and reactance (Xrs) from 0.25-16 Hz. Maximum (Rmax) and minimum (Rmin) resistances, static elastance (Est) and time constant (T) were computed by AOT. FOT and AOT data were interpreted with models featuring airway wall shunt, tissue viscoelasticity and parallel inhomogeneity. Rrs* and Xrs*, predicted from the AOT data, were computed and compared with Rrs and Xrs measured by FOT. Rrs and Xrs (hPa x s x L(-1)) decreased from 31.2+/-10.3 to 5.9+/-4.6 and increased from -20.3+/-7.1 to -8.0+/-4.4 from 0.25-16 Hz, respectively. Central resistance (Rc) and peripheral resistance (Rp) (in hPa x s x L(-1)), and shunt elastance (Esh) and tissue elastance (Et) (in hPa x L(-1)) were 4.4+/-5.4, 28.4+/-153, 723+/-393 and 31.8+/-10.1, respectively. Rmin, Rmax and Est were 18.4+/-5.9, 28.4+/-12.8 and 18.1+/-4.2 respectively, and T=0.76+/-0.25 s. The frequency dependence of predicted Rrs* and Xrs* differed markedly from that of measured Rrs and Xrs. The use of different models to interpret the measured data suggests that both airway and tissue properties determined the frequency dependence of respiratory resistance and respiratory reactance in ventilated chronic obstructive pulmonary disease patients at the investigated frequencies (0.25-16 Hz). |
| تدمد: | 1399-3003 0903-1936 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::283df9e02b6610b310277b5e548893b3 https://doi.org/10.1183/09031936.98.12010170 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....283df9e02b6610b310277b5e548893b3 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13993003 09031936 |
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