التفاصيل البيبلوغرافية
| العنوان: |
Preparation of Fluorescent Tubulin Binders |
| المؤلفون: |
Daniele Cartelli, Elena Riva, Graziella Cappelletti, Daniele Passarella, John S. Snaith, Stephen Faulkner, Martin Mattarella, Marcus Main, Daniel Sykes, Michael S. Christodoulou, Stella Borrelli |
| سنة النشر: |
2016 |
| مصطلحات موضوعية: |
Tubulin, Biochemistry, biology, Microtubule, Chemistry, biology.protein, General Chemistry, macromolecular substances, Fluorescence |
| الوصف: |
Thiocolchicine, taxol and cephalomannine have been used as building blocks for the preparation of four different fluorescent compounds designed to image the tubulin/microtubule network in cells. Thiocolchicine gave the best results and, in particular, the compound derived from conjugation with fluorescein minimally inhibits tubulin polymerization, is cell permeable and binds microtubules. Thus, it meets some of the demanding requirements for a new fluorescent dye that can secure a direct assay to evidence the tubulin/microtubules network in cells. © 2013 Wiley-VCH Verlag GmbH and Co. KGaA, Weinheim. |
| URL الوصول: |
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::286b36529839e33b6d5dbcf882a8b5a9
https://ora.ox.ac.uk/objects/uuid:4fcd4222-224b-4c8d-96b6-e39fcbc553ec |
| حقوق: |
OPEN |
| رقم الأكسشن: |
edsair.doi.dedup.....286b36529839e33b6d5dbcf882a8b5a9 |
| قاعدة البيانات: |
OpenAIRE |
