CD30-Positive T-Cell Lymphoproliferative Disorder of the Oral Mucosa—An Indolent Lesion: Report of 4 Cases
| العنوان: | CD30-Positive T-Cell Lymphoproliferative Disorder of the Oral Mucosa—An Indolent Lesion: Report of 4 Cases |
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| المؤلفون: | Monica Agarwal, Gillian Hall, Saumitra S Banerjee, N Pigadas, Philip Sloan, Patrick Shenjere, Robert W Blewitt |
| المصدر: | International Journal of Surgical Pathology. 16:286-290 |
| بيانات النشر: | SAGE Publications, 2008. |
| سنة النشر: | 2008 |
| مصطلحات موضوعية: | Adult, Male, Pathology, medicine.medical_specialty, CD30, T-Lymphocytes, T cell, Remission, Spontaneous, Ki-1 Antigen, Gene Rearrangement, T-Lymphocyte, Pathology and Forensic Medicine, Tongue, immune system diseases, hemic and lymphatic diseases, medicine, Humans, Lymphomatoid papulosis, Oral mucosa, Anaplastic large-cell lymphoma, Aged, Aged, 80 and over, integumentary system, business.industry, Mouth Mucosa, Gene rearrangement, Middle Aged, medicine.disease, Immunohistochemistry, Lymphoproliferative Disorders, Lymphoma, medicine.anatomical_structure, Female, Surgery, Anatomy, business |
| الوصف: | Four cases of CD30-positive T-cell lymphoproliferative disorder (CD30+ LPD) of the oral mucosa are described. This article aims to draw attention to this entity and to emphasize its usual benign clinical behavior despite its resemblance to T-cell lymphoma. All the patients were adults. Three of the lesions were on the dorsal surface of the tongue and 1 affected the buccal mucosa. All biopsies showed a dense lymphoid infiltrate composed of CD30+ atypical T cells with a polymorphous infiltrate in the background, which included eosinophils. In 1 case, monoclonal T-cell expansion was detected by molecular techniques. Three cases tested for Epstein—Barr virus were all negative. It is concluded that primary CD30+ T-cell LPD of the oral mucosa can be regarded as the oral counterpart of cutaneous CD30+ LPD such as lymphomatoid papulosis or anaplastic large cell lymphoma. Recognition of the condition is important to avoid overtreatment. |
| تدمد: | 1940-2465 1066-8969 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::287f7e805845c5e5bacb91746a4a82fa https://doi.org/10.1177/1066896907313755 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....287f7e805845c5e5bacb91746a4a82fa |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19402465 10668969 |
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