Management of gastric adenocarcinoma
| العنوان: | Management of gastric adenocarcinoma |
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| المؤلفون: | J. L. Arranz Cozar, G. Pérez Manga, B. Hernández Marín, V. M. Díaz Muñoz de la Espada, S. Encina García, Y. Izarzugaza Perón, P. Khosravi Shahi, P. García Alfonso |
| المصدر: | Clinical and Translational Oncology. 9:438-442 |
| بيانات النشر: | Springer Science and Business Media LLC, 2007. |
| سنة النشر: | 2007 |
| مصطلحات موضوعية: | Oncology, Cancer Research, medicine.medical_specialty, Bevacizumab, medicine.medical_treatment, Adenocarcinoma, Stomach Neoplasms, Internal medicine, medicine, Humans, Survival rate, Chemotherapy, Antibiotics, Antineoplastic, business.industry, General Medicine, digestive system diseases, Early Gastric Cancer, Survival Rate, Regimen, Treatment Outcome, Docetaxel, Drug Therapy, Combination, business, Injections, Intraperitoneal, Chemoradiotherapy, medicine.drug, Epirubicin |
| الوصف: | Gastric adenocarcinoma is the second most common cause of cancer death worldwide. The prognosis for patients with gastric adenocarcinoma depends on the stage of the disease at the time of diagnosis and treatment. Early gastric cancer, limited to the mucosa and submucosa, is best treated surgically and has a five-year survival rate of 70-95%. Surgical resection remains the primary curative treatment for localised disease. Despite this, the overall survival remains poor. The management of localised gastric adenocarcinoma is complex, and at present there is proven benefit of both preoperative chemotherapy and postoperative chemoradiotherapy. There is no standard regimen of chemotherapy for metastatic disease, although the regimen of ECF (epirubicin, cisplatin and fluorouracil) is the most used regimen, with a median survival of 7-9 months. With new regimens of chemotherapy, such as DCF (docetaxel, cisplatin and fluorouracil) or the combination of irinotecan, cisplatin and bevacizumab, the median survival has increased. Other new agents are under investigation. |
| تدمد: | 1699-3055 1699-048X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28873ae01aa8ec991ea42c6dc4903a0b https://doi.org/10.1007/s12094-007-0082-8 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....28873ae01aa8ec991ea42c6dc4903a0b |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 16993055 1699048X |
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