Hypokalaemic episodic polymyopathy in cats fed a vegetarian diet
| العنوان: | Hypokalaemic episodic polymyopathy in cats fed a vegetarian diet |
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| المؤلفون: | Levick Wr, Bain Sa, Leon A |
| المصدر: | Australian Veterinary Journal. 69:249-254 |
| بيانات النشر: | Wiley, 1992. |
| سنة النشر: | 1992 |
| مصطلحات موضوعية: | Male, Taurine, medicine.medical_specialty, Erythrocytes, Potassium, Glutamic Acid, chemistry.chemical_element, Hypokalemia, Cat Diseases, chemistry.chemical_compound, Glutamates, Muscular Diseases, Internal medicine, Animals, Urea, Medicine, Amino Acids, Myopathy, Creatine Kinase, Decreased urinary potassium, CATS, General Veterinary, business.industry, Diet, Vegetarian, Thiamine Deficiency, Muscle weakness, General Medicine, Dietary Potassium, Endocrinology, chemistry, Serum potassium, Creatinine, Cats, Female, Transketolase, medicine.symptom, business |
| الوصف: | A previously undocumented hypokalaemic condition with a cyclical nature, comprising acute bouts of polymyopathy followed by spontaneous recoveries, is described in the cat. Cats being fed a high protein vegetarian diet developed recurrent episodes of polymyopathy, characterised by ventroflexion of the head and neck, stiff forelimb gait, lateral head-resting and generalised muscle weakness. Plasma potassium concentrations (mean +/- standard deviation) were reduced from 3.28 +/- 0.33 mmol/l at the beginning of the experiment to 2.45 +/- 0.24 mmol/l during bouts of myopathy. This hypokalaemia was associated with increased creatine kinase activities indicative of muscle damage, and decreased urinary potassium concentrations, and was caused by insufficient dietary potassium. Cats that received the same diet supplemented with potassium did not develop hypokalaemic polymyopathy. Spontaneous recoveries of affected cats were not associated consistently with increases in plasma potassium concentrations. Plasma taurine concentrations decreased and glutamic acid increased markedly in all cats fed the experimental diet. There was no evidence of thiamin deficiency associated with the high glutamic acid intake. Veterinarians should be aware that hypokalaemic cats, and in particular those on potassium-deficient diets, may show cyclical disease with episodes of polymyopathy recurring after periods of spontaneous clinical recovery. This condition in cats may be a useful animal model for familial hypokalaemic periodic paralysis in humans. |
| تدمد: | 1751-0813 0005-0423 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29055f7ef5939f11dd30bf18f0be666c https://doi.org/10.1111/j.1751-0813.1992.tb09872.x |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....29055f7ef5939f11dd30bf18f0be666c |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17510813 00050423 |
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