Prevalence and Trends of Staphylococcus aureus Bacteraemia in Hospitalized Patients in South Africa, 2010 to 2012: Laboratory-Based Surveillance Mapping of Antimicrobial Resistance and Molecular Epidemiology
| العنوان: | Prevalence and Trends of Staphylococcus aureus Bacteraemia in Hospitalized Patients in South Africa, 2010 to 2012: Laboratory-Based Surveillance Mapping of Antimicrobial Resistance and Molecular Epidemiology |
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| المؤلفون: | Shareef Abrahams, Samantha Iyaloo, Warren Lowman, Adriano Duse, Halima Dawood, Colleen Bamford, Sharona Seetharam, Ranmini Kularatne, Yesholata Mahabeer, Nontombi Marylucy Mbelle, Prathna Bhola, Ashika Singh-Moodley, Olga Perovic, Jeannette Wadula, Noma Bosman |
| المساهمون: | Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences |
| المصدر: | PLoS ONE, Vol 10, Iss 12, p e0145429 (2015) PLoS ONE PLoS One |
| بيانات النشر: | Public Library of Science (PLoS), 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Meticillin, lcsh:Medicine, Bacteremia, Drug resistance, Antimicrobial resistance, medicine.disease_cause, Polymerase Chain Reaction, South Africa, Epidemiology, Prevalence, Child, lcsh:Science, Aged, 80 and over, Molecular Epidemiology, Antiinfective agent, Multidisciplinary, Antimicrobials, Middle Aged, Staphylococcal Infections, humanities, Hospitalization, Child, Preschool, Population Surveillance, Research Article, medicine.drug, Adult, Methicillin-Resistant Staphylococcus aureus, Staphylococcus aureus, medicine.medical_specialty, Adolescent, Genotype, Microbial Sensitivity Tests, Staphylococcal infections, Inhibitory Concentration 50, Young Adult, Age Distribution, Antibiotic resistance, Internal medicine, Nosocomial infections, medicine, Humans, Intensive care medicine, Aged, Molecular epidemiology, business.industry, lcsh:R, Infant, Newborn, Infant, medicine.disease, Methicillin-resistant Staphylococcus aureus, Methicillin Resistance, lcsh:Q, business, Cloning |
| الوصف: | Introduction We aimed to obtain an in-depth understanding on recent antimicrobial resistance trends and molecular epidemiology trends of S . aureus bacteraemia (SAB). METHODS: Thirteen academic centres in South Africa were included from June 2010 until July 2012. S . aureus susceptibility testing was performed on the MicroScan Walkaway. Real-time PCR using the LightCycler 480 II was done for mec A and nuc . SCC mec and spa -typing were finalized with conventional PCR. We selected one isolate per common spa type per province for multilocus sequence typing (MLST). RESULTS: S . aureus from 2709 patients were included, and 1231 (46%) were resistant to methicillin, with a significant decline over the three-year period (p-value = 0.003). Geographical distribution of MRSA was significantly higher in Gauteng compared to the other provinces (P |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1932-6203 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::292749fa2b3599d923d96a01968403d8 http://europepmc.org/articles/PMC4697812?pdf=render |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....292749fa2b3599d923d96a01968403d8 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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