أعرض في EDS

Potential role of FLT3-ligand in the angiogenic process of multiple myeloma

التفاصيل البيبلوغرافية
العنوان: Potential role of FLT3-ligand in the angiogenic process of multiple myeloma
المؤلفون: A. Antonakis, Constantina A. Pappa, Maria Kokonozaki, George Tsirakis, Maria Devetzoglou, M. Tzardi, S. Kyriakaki, Rodanthi Vyzoukaki, Michael G. Alexandrakis
المصدر: Leukemia research. 39(12)
سنة النشر: 2015
مصطلحات موضوعية: CD31, Male, Vascular Endothelial Growth Factor A, Cancer Research, medicine.medical_specialty, Angiogenesis, Receptors, Cell Surface, Dexamethasone, Bortezomib, fluids and secretions, Antigens, CD, Bone Marrow, hemic and lymphatic diseases, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Medicine, Humans, Cyclophosphamide, Melphalan, Multiple myeloma, Aged, Neoplasm Staging, Aged, 80 and over, Neovascularization, Pathologic, business.industry, Hepatocyte Growth Factor, Tumor Necrosis Factor-alpha, Endoglin, Membrane Proteins, hemic and immune systems, Hematology, Middle Aged, medicine.disease, Neoplasm Proteins, Haematopoiesis, medicine.anatomical_structure, Endocrinology, Oncology, embryonic structures, Microvessels, Prednisone, Female, Bone marrow, business, Multiple Myeloma, medicine.drug
الوصف: The aim of the study was to evaluate serum levels of FLT3-ligand (FLT3-L), a soluble molecule in bone marrow (BM), participating actively in hematopoiesis, in relation with angiogenic factors in multiple myeloma (MM) patients. We measured, in 70 patients with active MM and in 38 of them who responded to conventional therapy, serum levels of FLT3-L, along with known angiogenic factors, such as VEGF, endoglin, TNF-alpha and HGF (with ELISA) and BM microvascular density (MVD), estimating the immunohistochemical expression of CD31. All pre-treatment values were higher in active MM patients compared to controls (p
تدمد: 1873-5835
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29a191a8ea436486c82ff05063dacb8a
https://pubmed.ncbi.nlm.nih.gov/26521986
حقوق: CLOSED
رقم الأكسشن: edsair.doi.dedup.....29a191a8ea436486c82ff05063dacb8a
قاعدة البيانات: OpenAIRE
الوصف
تدمد:18735835