Closed-Incision Negative-Pressure Therapy in Obese Patients Undergoing Cesarean Delivery: A Randomized Controlled Trial
| العنوان: | Closed-Incision Negative-Pressure Therapy in Obese Patients Undergoing Cesarean Delivery: A Randomized Controlled Trial |
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| المؤلفون: | Jennifer Thompson, Geeta K. Swamy, Michael P. Smrtka, Ravindu Gunatilake, R.P. Heine, Leo R. Brancazio, Beverly Gray, Jennifer Gilner |
| المصدر: | AJP Reports American Journal of Perinatology Reports, Vol 07, Iss 03, Pp e151-e157 (2017) |
| بيانات النشر: | Thieme Medical Publishers, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | medicine.medical_specialty, obesity, medicine.medical_treatment, Case Report, Dehiscence, lcsh:Gynecology and obstetrics, law.invention, 03 medical and health sciences, 0302 clinical medicine, Hematoma, Randomized controlled trial, law, Negative-pressure wound therapy, Medicine, 030212 general & internal medicine, Adverse effect, lcsh:RG1-991, negative pressure wound therapy, business.industry, Obstetrics and Gynecology, medicine.disease, Surgery, 030220 oncology & carcinogenesis, Anesthesia, Seroma, Pediatrics, Perinatology and Child Health, wound infection, business, Complication, Body mass index, cesarean |
| الوصف: | Background Postcesarean wound morbidity is a costly complication of cesarean delivery for which preventative strategies remain understudied. Objective We compared surgical site occurrences (SSOs) in cesarean patients receiving closed-incision negative-pressure therapy (ciNPT) or standard-of-care (SOC) dressing. Study Design A single-center randomized controlled trial compared ciNPT (5–7 days) to SOC dressing (1–2 days) in obese women (body mass index [BMI] ≥ 35), undergoing cesarean delivery between 2012 and 2014. Participants were randomized 1:1 and monitored 42 ± 10 days postoperatively. The primary outcome SSOs included unanticipated local inflammation, wound infection, seroma, hematoma, dehiscence, and need for surgical or antibiotic intervention. Results Of the 92 randomized patients, 82 completed the study. ciNPT and SOC groups had similar baseline characteristics. Mean BMI was 46.5 ± 6.5 and no treatment-related serious adverse events. Compared with SOC, the ciNPT group had fewer SSOs (7/43 [16.3%] vs. 2/39 [5.1%], respectively; p = 0.16); significantly fewer participants with less incisional pain both at rest (39/46 [84.8%] vs. 20/46 [43.5%]; p Conclusion A trend in SSO reduction and a statistically significant reduction in postoperative pain and narcotic use was observed in women using ciNPT. |
| اللغة: | English |
| تدمد: | 2157-7005 2157-6998 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29f95df69f6cf216389fe8cdd1b54e4b http://europepmc.org/articles/PMC5511052 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....29f95df69f6cf216389fe8cdd1b54e4b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 21577005 21576998 |
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