Severe Non-Islet Cell Hypoglycemia From Ileum-Origin Gastrointestinal Stromal Tumor Producing Insulin-Like Growth Factor-2 in a Patient With Liver Cirrhosis Due to Chronic Hepatitis B
| العنوان: | Severe Non-Islet Cell Hypoglycemia From Ileum-Origin Gastrointestinal Stromal Tumor Producing Insulin-Like Growth Factor-2 in a Patient With Liver Cirrhosis Due to Chronic Hepatitis B |
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| المؤلفون: | Yuko Ono, Sho Furukawa, Koshi Hashimoto, Takenori Okumura, Takafumi Tsuchiya, Kohzo Takebayashi, Kenji Hara, Hiroyuki Shinozaki, Mio Kubo, Toshihiko Inukai, Mototaka Yamauchi, Atsushi Ujiie |
| المصدر: | Journal of Clinical Medicine Research |
| بيانات النشر: | Elmer Press, Inc., 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | medicine.medical_specialty, Cirrhosis, medicine.medical_treatment, Case Report, 030209 endocrinology & metabolism, 030204 cardiovascular system & hematology, Hypoglycemia, Gastroenterology, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Stromal tumor, geography, geography.geographical_feature_category, GiST, biology, business.industry, Steroid therapy, Insulin, NICTH, General Medicine, medicine.disease, Islet, Insulin-like growth factor 2, Liver cirrhosis, Prednisolone, biology.protein, business, GIST, medicine.drug |
| الوصف: | Non-islet cell tumor hypoglycemia (NICTH) is a rare paraneoplastic syndrome, and NICTH associated with gastrointestinal stromal tumor (GIST) is even more rare. Herein, we describe a patient with severe NICTH due to GIST who had developed liver cirrhosis as a consequence of chronic hepatitis B. Although circulating insulin, C-peptide, and insulin-like growth factor-1 (IGF-1) levels were significantly decreased, in contrast to our expectations, the growth hormone (GH) level was slightly elevated. Steroid therapy with prednisolone appeared to be effective for the prevention of severe and continuous hypoglycemia. |
| تدمد: | 1918-3011 1918-3003 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b29576ed45d7af4a31d34fe6d41d52c https://doi.org/10.14740/jocmr4326 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....2b29576ed45d7af4a31d34fe6d41d52c |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19183011 19183003 |
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