Impact of Infectious Complications on Survival and Recurrence of Patients With Stage II/III Colorectal Cancer: A Multicenter Retrospective Study
العنوان: | Impact of Infectious Complications on Survival and Recurrence of Patients With Stage II/III Colorectal Cancer: A Multicenter Retrospective Study |
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المؤلفون: | Hiroshi, Tamagawa, Toru, Aoyama, Masakatsu, Numata, Keisuke, Kazama, Yosuke, Atsumi, Kenta, Iguchi, Mihwa, Ju, Sho, Sawazaki, Sumito, Sato, Kazuki, Kano, Takashi, Ohshima, Takanobu, Yamada, Teni, Godai, Akio, Higuchi, Hiroyuki, Saeki, Norio, Yukawa, Yasushi, Rino |
المصدر: | Anticancer Research. 42:2763-2769 |
بيانات النشر: | Anticancer Research USA Inc., 2022. |
سنة النشر: | 2022 |
مصطلحات موضوعية: | Survival Rate, Cancer Research, Postoperative Complications, Oncology, Humans, Anastomotic Leak, General Medicine, Colorectal Neoplasms, Retrospective Studies |
الوصف: | Postoperative complications are associated with increased recurrence in colorectal cancer (CRC). We investigated the impact of infectious complications on the recurrence of CRC and overall survival after curative surgery in a single study group.In total, 1,668 patients who underwent radical resection for CRC in Yokohama City University, Yokohama Minami Kyosai Hospital, and Kanagawa Cancer Center between 2011 and 2019 were reviewed. Patients were classified into those with infectious complications (IC group) and those without infectious complications (Non-IC group). The risk factors for recurrence-free survival (RFS) and overall survival (OS) were analyzed.Postoperative complications were found in 560 of the 1,668 patients (33.5%), and IC, which occurred in 312 patients (18.7%), included pneumonia, anastomotic leakage, and intraperitoneal abscess. The 5-year OS rates in the Non-IC and IC groups were 95.5% and 90.4%, respectively, while the 5-year RFS rates were 74.4% and 68.1%, respectively. The multivariate analysis demonstrated that postoperative IC were significant independent risk factors for OS and RFS.The presence of postoperative IC after CRC resection is associated with decreased long-term survival. The surgical procedure, surgical strategy, and perioperative care should be carefully planned in order to avoid causing IC. |
تدمد: | 1791-7530 0250-7005 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b63aeeb3f94d257aec06378c401aea7 https://doi.org/10.21873/anticanres.15755 |
رقم الأكسشن: | edsair.doi.dedup.....2b63aeeb3f94d257aec06378c401aea7 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 17917530 02507005 |
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