ACE and ACTN3 genes polymorphisms among female Hungarian athletes in the aspect of sport disciplines
| العنوان: | ACE and ACTN3 genes polymorphisms among female Hungarian athletes in the aspect of sport disciplines |
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| المؤلفون: | M. Szmodis, Anna Protzner, J Pucsok, Miklós Tóth, Edit Bosnyák, I Györe, Emese Trájer, Anna Udvardy, Tímea Kováts, Zsolt Komka |
| المصدر: | Acta Physiologica Hungarica. 102:451-458 |
| بيانات النشر: | Akademiai Kiado Zrt., 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Adult, Genotype, Rowing, Athletic Performance, Peptidyl-Dipeptidase A, Young Adult, Polymorphism (computer science), Physiology (medical), Statistical significance, Humans, Medicine, Actinin, Allele, Allele frequency, Genotyping, Genetics, Hungary, Polymorphism, Genetic, biology, Athletes, business.industry, General Medicine, biology.organism_classification, Female, business, Sports |
| الوصف: | The aim of the study was to determine the importance of two sport-associated gene polymorphisms, alpha-actinin-3 R577X (ACTN3) and angiotensin-converting enzyme I/D (ACE), among Hungarian athletes in different sports. The examination was carried out only on women (n = 100). Sport-specific groups were formed in order to guarantee the most homogeneous clusters. Human genomic DNA was isolated from blood, and genotyping was performed by polymerase chain reaction. To measure the differences between the participating groups, Chi-squared test was performed using Statistica 9.0 for Windows® (significance level: p0.05). In comparing the ACE I/D allele frequencies, significant difference was detected between water polo (I = 61.11%; D = 38.89%) and combat sports (I = 35.71%, D = 64.29%) athletes (p0.03). There was no statistical difference when ACE I/D alleles in combat sports and kayaking/rowing (p0.05) were compared. A similarity was detectable in the I allele frequencies of the water polo (61.11%) and kayaking/rowing (56.67%) groups. The ACTN3 R/X polymorphism showed no differences in comparison with the sport groups. R allele frequencies were higher in every group compared to the X allele. The potential significance of the ACE I allele in sports of an aerobic nature was not clearly confirmed among Hungarian athletes. |
| تدمد: | 1588-2683 0231-424X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b69605809d7aa6bcbaa71e5237a2046 https://doi.org/10.1556/036.102.2015.4.12 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....2b69605809d7aa6bcbaa71e5237a2046 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15882683 0231424X |
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