Distribution of strain patterns in children with dilated cardiomyopathy
| العنوان: | Distribution of strain patterns in children with dilated cardiomyopathy |
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| المؤلفون: | Lukas A. J. Rammeloo, Liselotte M. Klitsie, Ronald B. Tanke, Willem A. Helbing, Michiel Dalinghaus, Arend D. J. ten Harkel, Ad P. C. M. Backx, Gideon J. du Marchie Sarvaas, Susanna L. den Boer, Gabriëlle G. van Iperen |
| المساهمون: | Pediatric surgery, ACS - Heart failure & arrhythmias, Paediatric Cardiology, Pediatrics, Faculteit Medische Wetenschappen/UMCG |
| المصدر: | Echocardiography, 34(6), 881-887. Wiley-Blackwell Echocardiography : a Journal of Cardiovascular Ultrasound and Allied Techniques, 34, 6, pp. 881-887 Echocardiography (Mount Kisco, N.Y.), 34(6), 881-887. Wiley-Blackwell den Boer, S L, du Marchie Sarvaas, G J, Klitsie, L M, van Iperen, G G, Tanke, R B, Helbing, W A, Backx, A P C M, Rammeloo, L A J, Dalinghaus, M & ten Harkel, A D J 2017, ' Distribution of strain patterns in children with dilated cardiomyopathy ', Echocardiography, vol. 34, no. 6, pp. 881-887 . https://doi.org/10.1111/echo.13548 Echocardiography, 34(6), 881-887 Echocardiography. A Journal of Cardiovascular Ultrasound and Allied Techniqu, 34(6), 881-887. Wiley-Blackwell Publishing Ltd Echocardiography-A journal of cardiovascular ultrasound and allied techniques, 34(6), 881-887. Wiley-Blackwell Echocardiography : a Journal of Cardiovascular Ultrasound and Allied Techniques, 34, 881-887 |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Cardiomyopathy, Dilated, Male, medicine.medical_specialty, Adolescent, medicine.medical_treatment, Heart Ventricles, Cardiac resynchronization therapy, Speckle tracking echocardiography, 030204 cardiovascular system & hematology, 03 medical and health sciences, 0302 clinical medicine, Predictive Value of Tests, Internal medicine, medicine, Humans, Radiology, Nuclear Medicine and imaging, 030212 general & internal medicine, Prospective Studies, Prospective cohort study, Child, LONGITUDINAL STRAIN, INDEX, Heart transplantation, Observer Variation, CARDIAC-RESYNCHRONIZATION THERAPY, OUTCOMES, CONGESTIVE-HEART-FAILURE, MECHANICAL DYSSYNCHRONY, business.industry, Proportional hazards model, Other Research Radboud Institute for Health Sciences [Radboudumc 0], Infant, Reproducibility of Results, Dilated cardiomyopathy, Heart, HEALTHY-CHILDREN, medicine.disease, dilated cardiomyopathy, medicine.anatomical_structure, Ventricle, Echocardiography, Heart failure, Child, Preschool, Cardiology, myocardial strain, Female, Cardiology and Cardiovascular Medicine, business, Follow-Up Studies |
| الوصف: | Objectives: This study aimed to evaluate the predicting value of quantitative and qualitative dyssynchrony parameters as assessed by two-dimensional speckle tracking echocardiography (STE) on outcome in children with dilated cardiomyopathy (DCM). Furthermore, the reproducibility of these parameters was investigated.Background: In previous studies in adults with heart failure, several dyssynchrony parameters have been shown to be a valuable predictor of clinical outcome.Methods: This multicenter, prospective study included 75 children with DCM and 75 healthy age-matched controls. Using STE, quantitative (time to global peak strain and parameters describing intraventricular time differences) and qualitative dyssynchrony parameters (pattern analysis) of the apical four-chamber, three-chamber, two-chamber views, and the short axis of the left ventricle were assessed. Cox regression was used to identify risk factors for the primary endpoints of death or heart transplantation. Inter-observer and intra-observer variability were described.Results: During a median of 21 months follow-up, 10 patients (13%) reached an endpoint. Although quantitative dyssynchrony measures were higher in patients as compared to controls, the inter-observer and intra-observer variability were high. Pattern analysis showed mainly reduced strain, instead of dyssynchronous patterns.Conclusions: In this study, quantitative dyssynchrony parameters were not reproducible, precluding their use in children. Qualitative pattern analysis showed predominantly reduced strain, suggesting that in children with DCM dyssynchrony may be a minor problem. |
| وصف الملف: | application/pdf |
| تدمد: | 0742-2822 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc15fffb8dc3e54c3dc48c6674e2301 https://doi.org/10.1111/echo.13548 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....2bc15fffb8dc3e54c3dc48c6674e2301 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 07422822 |
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