Tinea versicolor: Ultrastructural Studies on Hypopigmented and Hyperpigmented Skin

التفاصيل البيبلوغرافية
العنوان: Tinea versicolor: Ultrastructural Studies on Hypopigmented and Hyperpigmented Skin
المؤلفون: M Bou-Resli, R. Karaoui, A. Mousa, N S Al-Zaid
المصدر: Dermatology. 162:69-85
بيانات النشر: S. Karger AG, 1981.
سنة النشر: 1981
مصطلحات موضوعية: medicine.medical_specialty, Stratum granulosum, Skin Pigmentation, Dermatology, Hyperpigmented skin, Biology, Tinea Versicolor, medicine, Stratum corneum, Humans, Cytoskeleton, Skin, Hypopigmentation, Melanosome, Malassezia, integumentary system, Spores, Fungal, medicine.disease, Hyperpigmentation, Tinea versicolor, Microscopy, Electron, medicine.anatomical_structure, Microscopy, Electron, Scanning, Ultrastructure, Melanocytes, medicine.symptom
الوصف: Punch biopsy specimens from 4 patients with confirmed diagnosis of tinea versicolor were investigated. Hypopigmented, hyperigmented and uninvolved sites from the same subject were compared in relation to ultrastructural alterations as a result of infection with Malassezia furfur, by light, scanning, and transmission electron microscopy. Hyperpigmented skin had thicker stratum corneum than hypopigmented but both were thicker than the uninvolved skin. A large number of tonofilaments were noticed in hyperpigmented sites in stratum granulosum. In hypopigmented skin the melanosomes were individually dispersed and fewer in number than the uninvolved skin. In hyperpigmented skin, the melanosomes were sequestered in most cells suggesting difficulty in the transfer of melanosome granules to keratinocytes. In both cases of pigmentation the most readily affected parts of the cells were cyto-plasmic organelles with a latent effect on the nucleus and nucleolus. We postulate that either stage of pigmentation (hyperpigmentation or hypopigmentation) is an intermediary in nature as a result of M. furfur invasion.
تدمد: 1421-9832
1018-8665
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d1eed6717231ea3fa7bc55111f9c50e
https://doi.org/10.1159/000250253
حقوق: CLOSED
رقم الأكسشن: edsair.doi.dedup.....2d1eed6717231ea3fa7bc55111f9c50e
قاعدة البيانات: OpenAIRE